About: Clinical characteristics and outcomes of severe rhinovirus-associated pneumonia identified by bronchoscopic bronchoalveolar lavage in adults: Comparison with severe influenza virus-associated pneumonia

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About: Clinical characteristics and outcomes of severe rhinovirus-associated pneumonia identified by bronchoscopic bronchoalveolar lavage in adults: Comparison with severe influenza virus-associated pneumonia Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Clinical characteristics and outcomes of severe rhinovirus-associated pneumonia identified by bronchoscopic bronchoalveolar lavage in adults: Comparison with severe influenza virus-associated pneumonia
Creator	Kim, Sung-Han Choi, Sang-Ho Do, Kyung-Hyun Hong, Sang-Bum Koh, Younsuck Lee, Sang-Oh Lim, Chae-Man Sung, Heungsup Kim, Mi-Na Jeong, Jin-Yong Kim, Yang Lee, Ju Woo, Hee Huh, Jin
Source	Elsevier; Medline; PMC
abstract	BACKGROUND: Rhinoviruses (RVs) may cause pneumonia, but the characteristics of RV-associated pneumonia have not been adequately evaluated. OBJECTIVE: We aimed to compare characteristics, complications, and outcomes between severe RV- and influenza virus (IFV)-associated pneumonia in adults. STUDY DESIGN: We used prospective cohort data of adult patients with severe pneumonia who had been admitted to the medical intensive care unit of a tertiary care hospital over a 4-year period. The clinical features and outcomes of 27 patients with RV-positive bronchoscopic bronchoalveolar lavage (BAL) fluid were compared to those of 51 pneumonia patients with IFV-positive BAL fluid or IFV-positive nasopharyngeal specimens. RESULTS: Of 356 patients who underwent bronchoscopic BAL and respiratory virus polymerase chain reaction (PCR), RV was the most commonly identified virus (8.1%) from BAL fluid. Patients with RV-associated pneumonia were more likely to be immunocompromised than patients with IFV-associated pneumonia (81.5% vs. 33.3%, p < 0.001). Bacterial coinfection tended to be less common in the RV group (18.5% vs. 37.3%, p = 0.09). Although septic shock was less common in the RV group (29.6% vs. 54.9%, p = 0.03), other clinical manifestations, laboratory findings, and radiologic patterns were similar between the groups. The 28-day mortality of patients with severe RV- and IFV-associated pneumonia was similarly high (29.6% vs. 35.3% respectively, p = 0.61). CONCLUSIONS: Severe RV-associated pneumonia patients were more likely to be immunocompromised and less likely to present septic shock. Overall clinical features were similar and mortalities of both groups were comparably high. Studies of larger cohorts encompassing mild to moderate pneumonia patients are needed.
has issue date	2014-11-15(xsd:dateTime)
bibo:doi	10.1016/j.jcv.2014.11.010
bibo:pmid	25542469
has license	no-cc
sha1sum (hex)	8ed037050f9d1d900c65209bcc0587d10f980fe5
schema:url	https://doi.org/10.1016/j.jcv.2014.11.010
resource representing a document's title	Clinical characteristics and outcomes of severe rhinovirus-associated pneumonia identified by bronchoscopic bronchoalveolar lavage in adults: Comparison with severe influenza virus-associated pneumonia
has PubMed Central identifier	PMC7106464
has PubMed identifier	25542469
schema:publication	J Clin Virol
resource representing a document's body	covid:8ed037050f9d1d900c65209bcc0587d10f980fe5#body_text
is schema:about of	named entity 'patients' named entity 'bronchoscopic' named entity 'pneumonia' named entity 'severe' named entity 'pneumonia' named entity 'PRESENT' named entity 'OUTCOMES' named entity 'BRONCHOSCOPIC BRONCHOALVEOLAR LAVAGE' named entity 'INFLUENZA VIRUS' named entity 'IDENTIFIED BY' named entity 'ADULT' named entity 'IFV' named entity 'PNEUMONIA' named entity 'SPECIMENS' named entity 'DAY' named entity 'IDENTIFIED' named entity '2818' named entity 'GROUP' named entity 'BRONCHOSCOPIC BRONCHOALVEOLAR LAVAGE' named entity 'RHINOVIRUSES' named entity '356' named entity 'LABORATORY' named entity 'CLINICAL MANIFESTATIONS' named entity 'FLUID' named entity 'OUTCOMES' named entity 'MORTALITY' named entity 'BAL' named entity 'PATTERNS' named entity 'BACTERIAL' named entity 'MEDICAL INTENSIVE CARE UNIT' named entity 'BRONCHOSCOPIC' named entity 'RESPIRATORY VIRUS' named entity 'RESULTS' covid:arg/8ed037050f9d1d900c65209bcc0587d10f980fe5 named entity 'STUDY DESIGN' named entity 'YEAR' named entity 'MILD TO MODERATE' named entity 'NEEDED' named entity 'LARGER' named entity 'COINFECTION' named entity 'GROUPS' named entity 'CHARACTERISTICS' named entity 'COMMON' named entity 'CLINICAL CHARACTERISTICS' named entity 'ASSOCIATED' named entity 'RHINOVIRUS' named entity 'HIGH' named entity 'BUT' named entity '0.03' named entity 'POLYMERASE CHAIN REACTION' named entity 'PNEUMONIA' named entity 'ADULTS' named entity 'FINDINGS' named entity 'DATA' named entity '33.3' named entity 'CLINICAL FEATURES' named entity '0.001' named entity 'PATIENTS' named entity 'COMPARISON' named entity 'SEVERE' named entity 'SIMILAR' named entity 'PERIOD' named entity 'STUDIES' named entity 'COHORTS' named entity 'EVALUATED' named entity 'ADMITTED TO' named entity 'SEPTIC SHOCK' named entity 'ADULTS'

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