About: Comparison of respiratory pathogen yields from Nasopharyngeal/Oropharyngeal swabs and sputum specimens collected from hospitalized adults in rural Western Kenya

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About: Comparison of respiratory pathogen yields from Nasopharyngeal/Oropharyngeal swabs and sputum specimens collected from hospitalized adults in rural Western Kenya Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Comparison of respiratory pathogen yields from Nasopharyngeal/Oropharyngeal swabs and sputum specimens collected from hospitalized adults in rural Western Kenya
Creator	Onyango, Clayton Otieno, Nancy Widdowson, Marc-Alain Mott, Joshua Emukule, Gideon Njuguna, Henry Fields, Barry Lidechi, Shirley Ade, Fredrick Makokha, Caroline Nyaundi, Jeremiah Chaves, Sandra Winchell, Jonas Katieno, Jim Nyawanda, Bryan
Source	Medline; PMC
abstract	Molecular diagnostic methods are becoming increasingly available for assessment of acute lower respiratory illnesses (ALRI). However, nasopharyngeal/oropharyngeal (NP/OP) swabs may not accurately reflect etiologic agents from the lower respiratory tract where sputum specimens are considered as a more representative sample. The pathogen yields from NP/OP against sputum specimens have not been extensively explored, especially in tropical countries. We compared pathogen yields from NP/OP swabs and sputum specimens from patients ≥18 years hospitalized with ALRI in rural Western Kenya. Specimens were tested for 30 pathogens using TaqMan Array Cards (TAC) and results compared using McNemar’s test. The agreement for pathogen detection between NP/OP and sputum specimens ranged between 85–100%. More viruses were detected from NP/OP specimens whereas Klebsiella pneumoniae and Mycobacterium tuberculosis were more common in sputum specimens. There was no clear advantage in using sputum over NP/OP specimens to detect pathogens of ALRI in adults using TAC in the context of this tropical setting.
has issue date	2019-08-02(xsd:dateTime)
bibo:doi	10.1038/s41598-019-47713-4
bibo:pmid	31375774
has license	cc-by
sha1sum (hex)	8e9605de5913710c88b1107fd65dcc26ab372805
schema:url	https://doi.org/10.1038/s41598-019-47713-4
resource representing a document's title	Comparison of respiratory pathogen yields from Nasopharyngeal/Oropharyngeal swabs and sputum specimens collected from hospitalized adults in rural Western Kenya
has PubMed Central identifier	PMC6677726
has PubMed identifier	31375774
schema:publication	Sci Rep
resource representing a document's body	covid:8e9605de5913710c88b1107fd65dcc26ab372805#body_text
is schema:about of	named entity 'nasopharyngeal' named entity 'Specimens' named entity 'assessment' named entity 'Cards' named entity 'yields' named entity 'patients' named entity 'pathogens' named entity 'rural' named entity 'COMPARISON' named entity 'WESTERN' named entity 'SPECIMENS' named entity 'SWABS' covid:arg/8e9605de5913710c88b1107fd65dcc26ab372805 named entity 'TEST' named entity 'ADULTS' named entity 'ARRAY' named entity 'YEARS' named entity '27S' named entity 'REPRESENTATIVE SAMPLE' named entity 'RESULTS' named entity 'ACUTE' named entity 'KENYA' named entity 'ILLNESSES' named entity 'PATIENTS' named entity 'MYCOBACTERIUM TUBERCULOSIS' named entity 'AGREEMENT' named entity 'PATHOGENS' named entity 'REFLECT' named entity 'TESTED FOR' named entity 'CONSIDERED' named entity 'RURAL' named entity 'VIRUSES' named entity 'DETECTED' named entity 'TAQMAN' named entity 'ADVANTAGE' named entity 'TROPICAL' named entity 'LOWER' named entity 'HOSPITALIZED' named entity 'SWABS' named entity 'PATHOGEN DETECTION' named entity 'ADULTS' named entity 'MOLECULAR DIAGNOSTIC METHODS' named entity 'RESPIRATORY' named entity 'PATHOGEN' named entity 'SPUTUM' named entity 'COLLECTED' named entity 'HOSPITALIZED' named entity 'RURAL' named entity 'ASSESSMENT' named entity 'RESPIRATORY' named entity '100%' named entity 'LOWER RESPIRATORY TRACT' named entity 'WESTERN' named entity 'COUNTRIES' named entity 'HAVE' named entity 'COMMON' named entity 'KLEBSIELLA PNEUMONIAE' named entity 'WHERE' named entity 'NASOPHARYNGEAL' named entity 'CONTEXT' named entity 'TO DETECT' named entity 'SETTING' named entity 'USING' named entity 'KENYA' named entity 'AVAILABLE' named entity 'NASOPHARYNGEAL' named entity 'TAC'

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