About: Syrian Hamster as an Animal Model for the Study on Infectious Diseases

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About: Syrian Hamster as an Animal Model for the Study on Infectious Diseases Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Syrian Hamster as an Animal Model for the Study on Infectious Diseases
Creator	Miao, Jinxin Wang, Yaohe Wang, Zhimin Chard, Louisa Hsieh, Michael Khare, Prashant Matuschewski, Kai
Source	Medline; PMC
abstract	Infectious diseases still remain one of the biggest challenges for human health. In order to gain a better understanding of the pathogenesis of infectious diseases and develop effective diagnostic tools, therapeutic agents, and preventive vaccines, a suitable animal model which can represent the characteristics of infectious is required. The Syrian hamster immune responses to infectious pathogens are similar to humans and as such, this model is advantageous for studying pathogenesis of infection including post-bacterial, viral and parasitic pathogens, along with assessing the efficacy and interactions of medications and vaccines for those pathogens. This review summarizes the current status of Syrian hamster models and their use for understanding the underlying mechanisms of pathogen infection, in addition to their use as a drug discovery platform and provides a strong rationale for the selection of Syrian hamster as animal models in biomedical research. The challenges of using Syrian hamster as an alternative animal model for the research of infectious diseases are also addressed.
has issue date	2019-10-01(xsd:dateTime)
bibo:doi	10.3389/fimmu.2019.02329
bibo:pmid	31632404
has license	cc-by
sha1sum (hex)	8e29fa03ad2ae833e99f41652cc543877d415c44
schema:url	https://doi.org/10.3389/fimmu.2019.02329
resource representing a document's title	Syrian Hamster as an Animal Model for the Study on Infectious Diseases
has PubMed Central identifier	PMC6781508
has PubMed identifier	31632404
schema:publication	Front Immunol
resource representing a document's body	covid:8e29fa03ad2ae833e99f41652cc543877d415c44#body_text
is schema:about of	named entity 'ADDITION' named entity 'MODELS' named entity 'CHARACTERISTICS' named entity 'STUDY' named entity 'HUMANS' named entity 'BETTER' named entity 'CURRENT' named entity 'MODEL' named entity 'INFECTIOUS' named entity 'PATHOGENS' named entity 'BIOMEDICAL RESEARCH' named entity 'INFECTIOUS DISEASES' named entity 'THERAPEUTIC AGENTS' named entity 'GAIN' named entity 'DRUG DISCOVERY' named entity 'HUMAN HEALTH' named entity 'RATIONALE' named entity 'REVIEW' named entity 'PLATFORM' named entity 'TOOLS' named entity 'REQUIRED' named entity 'RESEARCH' named entity 'ALTERNATIVE' named entity 'MECHANISMS' named entity 'INFECTIOUS DISEASES' named entity 'SYRIAN HAMSTER' named entity 'VACCINES' named entity 'CHALLENGES' named entity 'UNDERLYING' named entity 'PROVIDES' named entity 'INTERACTIONS' named entity 'PATHOGEN' named entity 'USE' named entity 'REPRESENT' named entity 'STRONG' named entity 'PATHOGENESIS' named entity 'VIRAL AND' named entity 'SIMILAR' named entity 'POST' named entity 'ORDER' named entity 'ASSESSING' named entity 'INFECTION' named entity 'MEDICATIONS AND VACCINES' named entity 'ANIMAL MODEL' named entity 'IMMUNE RESPONSES' named entity 'PREVENTIVE' named entity 'SELECTION' named entity 'UNDERSTANDING' named entity 'SYRIAN HAMSTER' named entity 'THEIR' named entity 'EFFICACY' named entity 'USING' named entity 'EFFECTIVE' named entity 'DIAGNOSTIC' named entity 'BACTERIAL' named entity 'STATUS' named entity 'PARASITIC' named entity 'SUITABLE' named entity 'ONE OF' named entity 'ANIMAL MODEL' named entity 'INCLUDING' covid:arg/8e29fa03ad2ae833e99f41652cc543877d415c44 named entity 'pathogenesis' named entity 'Syrian hamster' named entity 'animal models' named entity 'pathogens' named entity 'immune responses' named entity 'pathogen' named entity 'Syrian hamster' named entity 'pathogens' named entity 'Animal Model' named entity 'Syrian hamster' named entity 'abscesses' named entity 'hamster' named entity 'Syrian hamsters'

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