About: Long term stability and infectivity of herpesviruses in water

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Long term stability and infectivity of herpesviruses in water
Creator	Osterrieder, Nikolaus Damiani, Armando Greenwood, Alex Bischofberger, Sebastian Dayaram, Anisha Franz, Mathias Schattschneider, Alexander
Source	PMC
abstract	For viruses to utilize environmental vectors (hard surfaces, soil, water) for transmission, physical and chemical stability is a prerequisite. There are many factors including pH, salinity, temperature, and turbidity that are known to contribute to the ability of viruses to persist in water. Equine herpesvirus type-1 (EHV-1) is a pathogenic alphaherpesvirus associated with domestic horses and wild equids. EHV-1 and recombinants of EHV-1 and EHV-9 are able to cause infections in non-equid animal species, particularly in captive settings. Many of the captive non-equid mammals are not naturally sympatric with equids and do not share enclosures, however, in many cases water sources may overlap. Similarly, in the wild, equids encounter many species at waterholes in times of seasonal drought. Therefore, we hypothesized that EHV-1 is stable in water and that water may act as a vector for EHV-1. In order to establish the conditions promoting or hindering EHV-1 longevity, infectivity and genomic stability in water; we exposed EHV-1 to varied water environments (pH, salinity, temperature, and turbidity) in controlled experiments over 21 days. The presence and infectivity of the virus was confirmed by both qPCR and cell culture experiments. Our results show that EHV-1 remains stable and infectious under many conditions in water for up to three weeks.
has issue date	2017-04-21(xsd:dateTime)
bibo:doi	10.1038/srep46559
bibo:pmid	28429732
has license	cc-by
sha1sum (hex)	8dc2ba0eb167ca45f16ad38f1d0cca36228ce28f
schema:url	https://doi.org/10.1038/srep46559
resource representing a document's title	Long term stability and infectivity of herpesviruses in water
has PubMed Central identifier	PMC5399353
has PubMed identifier	28429732
schema:publication	Sci Rep
resource representing a document's body	covid:8dc2ba0eb167ca45f16ad38f1d0cca36228ce28f#body_text
is schema:about of	named entity 'Our' named entity 'environmental' named entity 'herpesvirus' named entity 'water' named entity 'infectivity' named entity 'wild' named entity 'weeks' named entity 'genomic' named entity 'IS A' named entity 'PRESENCE' named entity 'VIRUSES' named entity 'infectivity' named entity 'controlled experiments' named entity 'longevity' named entity 'viruses' named entity 'stable' named entity 'water' named entity 'turbidity' named entity 'waterholes' named entity 'infections' named entity 'promoting' named entity 'infectivity' named entity 'recombinants' named entity 'Equine' named entity 'equids' named entity 'qPCR' named entity 'infectivity' named entity 'EHV-1' named entity 'mammals' named entity 'controlled experiments' named entity 'turbidity' named entity 'drought' named entity 'animal species' named entity 'EHV-1' named entity 'equid' named entity 'equids' named entity 'Long term' named entity 'hard' named entity 'cell culture' named entity 'molecular techniques' named entity 'kanamycin' named entity 'EDTA' named entity 'qPCR' named entity 'EHV-1' named entity 'equids' named entity 'EHV-1' named entity 'EHV-1' named entity '21 days' named entity 'Varicellovirus' named entity 'virus' named entity 'tissue culture' named entity 'viral DNA' named entity 'EHV-1' named entity 'viral replication' named entity 'response variable' named entity 'brackish' named entity 'pathogens' named entity 'phosphate-buffered saline' named entity 'sediment' named entity 'herpesviruses' named entity 'sediment' named entity 'sediment' named entity 'cell culture' named entity 'enteric viruses' named entity 'turbidity' named entity 'wild animals' named entity 'EHV-1' named entity 'UV light' named entity 'EHV-1' named entity 'mixed species assemblages' named entity 'viruses' named entity 'equids' named entity 'GCN' named entity 'pH 8' named entity 'pseudorabies virus'

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