About: Posttransfusion Non-A, Non-B Hepatitis: Physicochemical Properties of Two Distinct Agents

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Posttransfusion Non-A, Non-B Hepatitis: Physicochemical Properties of Two Distinct Agents
Creator	Maynard, J Bradley, D Cook, E Ebert, J Fields, H Mccaustland, K Popper, H Schable, C
Source	PMC
abstract	Two separate and distinct episodes of non-At non-B hepatitis were induced in each of two chimpanzees by two inocula: one containing a chloroform-resistant agent and the other containing a chloroform-sensitive agent. Both agents were recovered from liver tissue and plasma obtained from a single chimpanzee during the acute and chronic phases of infection with a factor VIII concentrate, respectively. The chloroform-resistant agent did not cause unique changes in hepatocytes; in contrast, the chloroform-sensitive agent did induce the formation of cytoplasmic tubules, convoluted endoplasmic reticulum, and dense reticular inclusion bodies. The latter changes are similar in character to those induced in infected cells by some enveloped mammalian RNA viruses.
has issue date	1983-08-01(xsd:dateTime)
bibo:doi	10.1093/infdis/148.2.254
bibo:pmid	6411832
has license	no-cc
sha1sum (hex)	8c64558dbf212fcc80b2aeb751d2bc37614f4aa9
schema:url	https://doi.org/10.1093/infdis/148.2.254
resource representing a document's title	Posttransfusion Non-A, Non-B Hepatitis: Physicochemical Properties of Two Distinct Agents
has PubMed Central identifier	PMC7109850
has PubMed identifier	6411832
schema:publication	J Infect Dis
resource representing a document's body	covid:8c64558dbf212fcc80b2aeb751d2bc37614f4aa9#body_text
is schema:about of	named entity 'induced' named entity 'acute' named entity 'INDUCE' named entity 'LIVER TISSUE' named entity 'chimpanzees' named entity 'Physicochemical' named entity 'factor VIII' named entity 'infection' named entity 'chloroform' named entity 'Physicochemical Properties' named entity 'induced' named entity 'HBV' named entity 'ultrastructural' named entity 'virus' named entity 'chimpanzee' named entity 'hepatitis' named entity 'liver' named entity 'Plasma' named entity '10.0' named entity 'liver' named entity 'chimpanzees' named entity 'fibrosis' named entity 'chimpanzees' named entity 'inoculum' named entity 'viral hepatitis' named entity 'poliovirus' named entity 'liver biopsy' named entity 'chimpanzees' named entity 'inoculation' named entity 'EDTA' named entity 'hepatitis' named entity 'infectious agent' named entity 'serologic' named entity 'inoculum' named entity 'chimpanzees' named entity 'EDTA' named entity 'liver tissue' named entity 'inoculum' named entity 'hepatocytes' named entity 'incubation period' named entity 'homogenate' named entity 'factor VIII' named entity 'liver' named entity 'inoculum' named entity 'hepatitis' named entity 'hepatitis' named entity 'chloroform' named entity 'inoculum' named entity 'density gradient' named entity 'hepatitis' named entity 'buoyant' named entity 'inclusion bodies' named entity 'plasma' named entity 'viral hepatitis' named entity 'antigen' named entity '0 hr' named entity 'plasma' named entity 'liver biopsy' named entity 'PBS' named entity 'cytomegalovirus' named entity 'inoculum' named entity 'cesium chloride' named entity 'Electron microscopic' named entity 'chimpanzee' named entity 'liver biopsy' named entity 'needle aspiration' named entity 'inclusion bodies' named entity 'EBV' named entity 'phosphate' named entity 'infection' named entity 'electron microscopy' named entity 'inoculum' named entity 'cytoplasmic' named entity 'parainfluenza virus'

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