About: Self-collection: an appropriate alternative during the SARS-CoV-2 pandemic

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About: Self-collection: an appropriate alternative during the SARS-CoV-2 pandemic Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Self-collection: an appropriate alternative during the SARS-CoV-2 pandemic
Creator	Brown, Suzanne Bursle, Evan Byrne, Shane Chong, Smathi Hadlow, Narelle Hanly, F Moir, Douglass New, David Newcombe, James Robson, Jennifer Siversten, Terri Wehrhahn, Michael
Source	Elsevier; Medline; PMC
abstract	OBJECTIVES: To evaluate the reliability of self-collection for SARS-CoV-2 and other respiratory viruses because swab collections for SARS-CoV-2 put health workers at risk of infection and require use of personal protective equipment (PPE). METHODS: In a prospective study, patients from two states in Australia attending dedicated COVID-19 collection clinics were offered the option to first self-collect (SC) throat and nasal swabs (SCNT) prior to health worker collect (HC) using throat and nasal swabs (Site 1) or throat and nasopharyngeal swabs (Site 2). Samples were analysed for SARS-CoV-2 as well as common respiratory viruses. Concordance of results between methods was assessed using Cohen's kappa (κ) and Cycle threshold (Ct) values were recorded for all positive results as a surrogate measure for viral load. RESULTS: Of 236 patients sampled by HC and SC, 25 had SARS-CoV-2 (24 by HC and 25 by SC) and 63 had other respiratory viruses (56 by HC and 58 y SC). SC was highly concordant with HC (κ = 0.890) for all viruses including SARS-CoV-2 and more concordant than HC to positive results by any method (κ = 0.959 vs 0.933). Mean SARS-CoV-2 E-gene and N-gene, rhinovirus and parainfluenza Ct values did not differ between HC and SCNT. CONCLUSIONS: Self-collection of throat and nasal swabs offers a reliable alternative to health worker collection for the diagnosis of SARS-CoV-2 and other respiratory viruses and provides patients with easier access to testing, reduces exposure of the community and health workers to those being tested and reduces requirement for PPE.
has issue date	2020-05-04(xsd:dateTime)
bibo:doi	10.1016/j.jcv.2020.104417
bibo:pmid	32403007
has license	no-cc
sha1sum (hex)	8b87dbd95aab711d9a65a7f02e870f76cc50e344
schema:url	https://doi.org/10.1016/j.jcv.2020.104417
resource representing a document's title	Self-collection: an appropriate alternative during the SARS-CoV-2 pandemic
has PubMed Central identifier	PMC7198188
has PubMed identifier	32403007
schema:publication	J Clin Virol
resource representing a document's body	covid:8b87dbd95aab711d9a65a7f02e870f76cc50e344#body_text
is schema:about of	named entity 'swab' named entity 'SARS-CoV-2' named entity 'WORDS' named entity 'EVIDENCE OF' named entity 'PERSONAL PROTECTIVE EQUIPMENT' named entity 'PRESERVE' named entity 'SELF' named entity 'viruses' named entity 'perform' named entity 'Running' named entity 'Journal' named entity 'SARS-CoV-2' named entity 'SARS-CoV-2' named entity 'SCNT' named entity 'CDNA' named entity 'SARS-CoV-2' named entity 'SARS-CoV-2' named entity 'World Health Organisation' named entity 'viruses' named entity 'SARS-CoV-2' named entity 'COVID' named entity 'random effect' named entity 'viral load' named entity 'bronchoalveolar lavage fluid' named entity 'viral load' named entity 'COVID' named entity 'viruses' named entity 'SARS-CoV-2' named entity 'viruses' named entity 'respiratory tract' named entity 'COVID' named entity 'SARS-CoV-2' named entity 'SCNT' named entity 'respiratory syncytial virus' named entity 'nasopharyngeal' named entity 'infection' named entity 'RSV' named entity 'rhinovirus' named entity 'mixed effects models' named entity 'SARS-CoV-2' named entity 'viruses' named entity 'oropharyngeal' named entity 'aspirate' named entity 'COVID-19' named entity 'respiratory tracts' named entity 'PPE' named entity 'SARS-CoV-2' named entity 'influenza' named entity 'COVID' named entity 'PPE' named entity 'gene' named entity 'COVID' named entity 'asymptomatic patients' named entity 'SCNT' named entity 'SARS-CoV-2' named entity 'March 2020' named entity 'COVID-19 pandemic' named entity 'viruses' named entity 'SARS-CoV-2' named entity 'SCNT' named entity 'not-for-profit' named entity 'asymptomatic' named entity 'sample size' named entity 'meta-analysis' named entity 'viral load' named entity 'regression analyses' named entity 'SARS-CoV-2' named entity 'SCNT' named entity 'human coronaviruses' named entity 'gene'

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