About: Sequence analysis of gene 3, gene 4 and gene 5 of avian infectious bronchitis virus strain CU-T2

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About: Sequence analysis of gene 3, gene 4 and gene 5 of avian infectious bronchitis virus strain CU-T2 Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Sequence analysis of gene 3, gene 4 and gene 5 of avian infectious bronchitis virus strain CU-T2
Creator	Jia, Wei Naqi, Syed
Source	Elsevier; Medline; PMC
abstract	Abstract We have previously reported the nucleotide sequences of gene 2 (spike (S) protein gene), gene 6 (nucleocapsid (N) protein gene), and the 3′ end untranslated region of a novel avian infectious bronchitis virus (IBV) strain, CU-T2 [Jia et al. (1995) Arch. Virol. 140, 259–271]. In the present report we describe the sequences of the remaining genes of this strain (gene 3, 4 and 5) with the exception of gene 1 (RNA polymerase gene). Gene 3 contained three open reading frames (ORFs), 3a, 3b and 3c of 174, 195 and 282 nucleotides (nt), respectively. Gene 4 (membrane (M) protein gene) consisted of 749 nt with a single ORF of 687 nt. Gene 5 contained two ORFs, 5a and 5b, with 198 and 249 nt, respectively. Thus, in total, there were 7349 nt from the 5′ end of S protein gene to the 3′ end of the CU-T2 genome. The overall nt sequence homologies between gene 3, 4, and 5 of CU-T2 and those of other strains were between 84.1–90.8%, 85.8–88.8% and 90.4–96.4%, respectively. The predicted amino acid (aa) sequence homologies revealed that gene 3b and 5b were more conserved than 3a, 3c and 5a. Each individual gene of CU-T2 strain (with the exception of the RNA polymerase gene) had a different level of homology with the homologous gene of other strains, suggesting that the evolution of IBV strains in general has been a complex, and as yet, poorly understood process. © 1997 Elsevier Science B.V. All rights reserved.
has issue date	1997-04-21(xsd:dateTime)
bibo:doi	10.1016/s0378-1119(96)00847-5
bibo:pmid	9168126
has license	els-covid
sha1sum (hex)	8a197b4ea338d5b8ab1c33253857d79b70b35a98
schema:url	https://doi.org/10.1016/s0378-1119%2896%2900847-5
resource representing a document's title	Sequence analysis of gene 3, gene 4 and gene 5 of avian infectious bronchitis virus strain CU-T2
has PubMed Central identifier	PMC7125653
has PubMed identifier	9168126
schema:publication	Gene
resource representing a document's body	covid:8a197b4ea338d5b8ab1c33253857d79b70b35a98#body_text
is schema:about of	named entity 'strains' named entity 'exception' named entity 'revealed' named entity 'gene' named entity 'protein' named entity 'predicted' named entity 'OVERALL' named entity 'NOVEL' named entity '282' named entity 'STRAINS' named entity 'SEQUENCE' named entity 'PREVIOUSLY' named entity 'POLYMERASE GENE' named entity '195' named entity 'REPORTED' named entity '140' named entity 'END' named entity 'AMINO ACID' named entity 'UNDERSTOOD' named entity 'CONSERVED' named entity 'VIROL' named entity 'REPORT' named entity 'PROCESS' named entity '174' named entity 'POORLY' named entity '749' named entity 'PREDICTED' named entity 'ARCH' named entity 'LEVEL' named entity 'NUCLEOTIDES' named entity 'DESCRIBE' named entity 'EXCEPTION' named entity 'NUCLEOTIDE SEQUENCES' named entity '28S' named entity 'TOTAL' named entity 'SCIENCE' named entity 'GENERAL' named entity 'AVIAN INFECTIOUS BRONCHITIS VIRUS' named entity 'GENE' named entity 'STRAIN' named entity 'AVIAN INFECTIOUS BRONCHITIS VIRUS' named entity '1997' named entity 'CONTAINED' named entity 'GENES' named entity 'REMAINING' named entity 'HOMOLOGY' named entity 'RNA POLYMERASE' named entity 'COMPLEX' named entity 'SEQUENCES' named entity 'EVOLUTION' named entity '7349' named entity 'SINGLE' named entity 'OPEN READING FRAMES' named entity 'UNTRANSLATED REGION' named entity 'INDIVIDUAL' named entity 'HOMOLOGOUS GENE' named entity 'DIFFERENT' named entity 'STRAIN' named entity 'SEQUENCE ANALYSIS' named entity 'REVEALED' named entity 'GENOME' named entity 'ORF' named entity 'S PROTEIN' named entity 'PRESENT' named entity 'PROTEIN GENE' named entity 'HAVE' covid:arg/8a197b4ea338d5b8ab1c33253857d79b70b35a98 named entity 'level' named entity 'gene' named entity 'total' named entity 'Each' named entity 'IBV' named entity 'protein' named entity 'polymerase' named entity 'Arch' named entity 'Gene' named entity 'strain' named entity 'sequences' named entity 'gene' named entity 'gene'

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