About: Human Bocavirus Infection in Young Children in the United States: Molecular Epidemiological Profile and Clinical Characteristics of a Newly Emerging Respiratory Virus

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About: Human Bocavirus Infection in Young Children in the United States: Molecular Epidemiological Profile and Clinical Characteristics of a Newly Emerging Respiratory Virus Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Human Bocavirus Infection in Young Children in the United States: Molecular Epidemiological Profile and Clinical Characteristics of a Newly Emerging Respiratory Virus
Creator	Ferguson, David Weibel, Carla Vazquez, Marietta Kahn, Jeffrey Landry, Marie Shapiro, Eugene Kesebir, Deniz
source	Medline; PMC
abstract	BackgroundHuman bocavirus (HBoV) is a newly identified human parvovirus that was originally identified in the respiratory secretions of children with respiratory tract disease. To further investigate the epidemiological profile and clinical characteristics of HBoV infection, we screened infants and children <2 years of age (hereafter referred to as “children”) for HBoV MethodsChildren for whom respiratory specimens submitted to a diagnostic laboratory tested negative for respiratory syncytial virus, parainfluenza viruses (types 1–3), influenza A and B viruses, and adenovirus, as well as asymptomatic children, underwent screening for HBoV by use of polymerase chain reaction (PCR). Respiratory specimens were obtained from the children from 1 January 2004 through 31 December 2004 ResultsTwenty-two (5.2%) of the 425 children who had a respiratory specimen submitted to the diagnostic laboratory and 0 of the 96 asymptomatic children were found to be positive for HBoV by PCR (P=.02). Fever, rhinorrhea, cough, and wheezing were observed in ⩾50% of the HBoV-positive children. Of the 17 children who had chest radiography performed, 12 (70.6%) had abnormal findings. HBoV appeared to have a seasonal distribution. Nucleotide polymorphisms were detected in the viral capsid protein (VP) 1/VP2 genes. Two distinct HBoV genotypes circulated during the study period ConclusionsHBoV is circulating in the United States and is associated with both upper and lower respiratory tract disease in infants and young children
has issue date	2006-11-01(xsd:dateTime)
bibo:doi	10.1086/508213
bibo:pmid	17041854
has license	no-cc
sha1sum (hex)	888fcede2aa9a27156ae87e74c1d3008d0c583fb
schema:url	https://doi.org/10.1086/508213
resource representing a document's title	Human Bocavirus Infection in Young Children in the United States: Molecular Epidemiological Profile and Clinical Characteristics of a Newly Emerging Respiratory Virus
has PubMed Central identifier	PMC7204143
has PubMed identifier	17041854
schema:publication	J Infect Dis
resource representing a document's body	covid:888fcede2aa9a27156ae87e74c1d3008d0c583fb#body_text
is schema:about of	named entity 'Emerging' named entity 'Infection' named entity 'Characteristics' named entity 'Virus' named entity 'Young Children' named entity 'genomic sequences' named entity 'PCR' named entity 'gene' named entity 'pathogen' named entity 'asymptomatic' named entity 'virus' named entity 'amplificatio' named entity 'HBoV' named entity 'nucleotide' named entity 'HBoV' named entity 'HBoV' named entity 'human metapneumovirus' named entity 'amplicon' named entity 'asymptomatic' named entity 'HBoV' named entity 'HBoV' named entity 'HBoV' named entity 'Clinical Virology' named entity 'viruses' named entity 'asymptomatic' named entity 'Parvovirinae' named entity 'intensive care' named entity 'polymorphism' named entity 'HBoV' named entity 'HBoV' named entity 'genus' named entity 'HBoV' named entity 'WBC' named entity 'Bocavirus' named entity 'Southern Hemisphere' named entity 'amplificatio' named entity 'nonstructural protein' named entity 'VP1' named entity 'minute virus of canines' named entity 'viruses' named entity 'urgent care' named entity 'viruses' named entity 'Parvoviridae' named entity 'HBoV' named entity 'respiratory tract' named entity 'binding sites' named entity 'urine' named entity 'HBoV' named entity 'HBoV' named entity 'Fisher's exact test' named entity 'culture results' named entity 'PCR' named entity 'VP1' named entity 'polymorphism' named entity 'parvovirus B19' named entity 'gene' named entity 'phylogenetic analysis' named entity 'Nosocomial infection' named entity 'HBoV' named entity 'respiratory tract' named entity 'genotypes' named entity 'HBoV' named entity 'chest radiography' named entity 'primer' named entity 'antigen' named entity 'VP1' named entity 'United States' named entity 'New Haven, Connecticut' named entity 'viruses' named entity 'adenovirus' named entity 'HBoV' named entity 'gastrointestinal disease' named entity 'clinical characteristics' named entity 'lower respiratory tract' named entity 'early spring'

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