About: Photosensitizing potential of tailored magnetite hybrid nanoparticles functionalized with levan and zinc (II) phthalocyanine

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Photosensitizing potential of tailored magnetite hybrid nanoparticles functionalized with levan and zinc (II) phthalocyanine Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Photosensitizing potential of tailored magnetite hybrid nanoparticles functionalized with levan and zinc (II) phthalocyanine
Creator	Chelminiak-Dudkiewicz, Dorota Goslinski, Tomasz Ilnicka, Anna Marszałł, Michał Mlynarczyk, Dariusz Rybczynski, Patryk Smolarkiewicz-Wyczachowski, Aleksander Wegrzynowska-Drzymalska, Katarzyna Ziegler-Borowska, Marta Chelminiak-Dudkiewicz, D Goslinski, T Ilnicka, A Marszał, M Marszał, Michał Mlynarczyk, D Rybczynski, P Smolarkiewicz-Wyczachowski, A Wegrzynowska-Drzymalska, K Ziegler-Borowska, M
Source	Elsevier; Medline; PMC
abstract	Abstract Phototherapies, including photodynamic therapy (PDT), have been widely used in the treatment of various diseases, especially for cancer. However, there is still a lack of effective, safe photosensitizers that would be well tolerated by patients. The combination of several methods (like phototherapy and hyperthermia) constitutes a modern therapeutic approach, which demands new materials based on components that are non-toxic without irradiation. Therefore, this study presents the synthesis and properties of novel, advanced nanomaterials in which the advantage features of the magnetic nanoparticles and photoactive compounds were combined. The primary purpose of this work was the synthesis of magnetic nanoparticles coated with biocompatible and antitumor polysaccharide - levan, previously unknown from scientific literature, and the deposition of potent photosensitizer – zinc(II) phthalocyanine on their surface. In order to better characterize the nature of the coating covering the magnetic core, the atomic force microscope analysis, a contact angle measurement, and the mechanical properties of pure levan and its blend with zinc(II) phthalocyanine films were investigated. This magnetic nanomaterial revealed the ability to generate singlet oxygen upon exposure to light. Finally, preliminary toxicity of obtained nanoparticles was tested using the Microtox® test – with and without irradiation.
has issue date	2020-05-07(xsd:dateTime)
bibo:doi	10.1016/j.apsusc.2020.146602
bibo:pmid	32382204
has license	els-covid
sha1sum (hex)	8838896efa2472e52d9d70914b80172a415556ba
schema:url	https://doi.org/10.1016/j.apsusc.2020.146602
resource representing a document's title	Photosensitizing potential of tailored magnetite hybrid nanoparticles functionalized with levan and zinc (II) phthalocyanine
has PubMed Central identifier	PMC7204711
has PubMed identifier	32382204
schema:publication	Appl Surf Sci
resource representing a document's body	covid:8838896efa2472e52d9d70914b80172a415556ba#body_text
is schema:about of	named entity 'tested' named entity 'tolerated' named entity 'Journal' covid:arg/8838896efa2472e52d9d70914b80172a415556ba named entity 'materials' named entity 'antitumor' named entity 'phthalocyanine' named entity 'based' named entity 'coated' named entity 'magnetic core' named entity 'PDT' named entity 'photoactive' named entity 'contact angle' named entity 'antitumor' named entity 'nanomaterials' named entity 'levan' named entity 'hyperthermia' named entity 'atomic force microscope' named entity 'singlet oxygen' named entity 'phthalocyanine' named entity 'zinc' named entity 'zinc' named entity 'nanoparticles' named entity 'spinel' named entity 'Polysaccharides' named entity 'levan' named entity 'solvent' named entity 'PDT' named entity 'room temperature' named entity 'contact angle' named entity 'magnetic nanoparticles' named entity 'antimicrobial therapy' named entity 'photosensitizer' named entity 'magnetization' named entity 'irradiation' named entity 'weight loss' named entity 'irradiation' named entity 'sodium alginate' named entity 'hydrophobic' named entity 'pharmaceutical' named entity 'polar liquid' named entity 'polysaccharide' named entity 'singlet oxygen' named entity 'deionized water' named entity 'absorbance' named entity 'Zinc' named entity 'composites' named entity 'morphology' named entity 'quantum yield' named entity 'density functional theory' named entity 'nanoparticles' named entity 'ophthalmic' named entity 'toxicity' named entity 'zinc' named entity 'ROS' named entity 'antitumor agent' named entity 'magnetic core' named entity 'epichlorohydrin' named entity 'carbohydrates' named entity 'biocompatibility' named entity 'polymers' named entity 'levan' named entity 'levan'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software