About: Efficient smooth muscle cell differentiation of iPS cells on curcumin-incorporated chitosan/collagen/polyvinyl-alcohol nanofibers

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Efficient smooth muscle cell differentiation of iPS cells on curcumin-incorporated chitosan/collagen/polyvinyl-alcohol nanofibers Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Efficient smooth muscle cell differentiation of iPS cells on curcumin-incorporated chitosan/collagen/polyvinyl-alcohol nanofibers
Creator	Ardeshirylajimi, Abdolreza Mir, & Taheri, Mohammad Basiri, Abbas Mokhames, Zakiye Omrani, Davood Rezaie, Zahra
Source	PMC
abstract	Bladder dysfunction is one of the most common diseases that occur for a number of reasons and the current treatment modalities do not improve much in its recovery process. Tissue engineering in the last two decades has given great hope for the treatment of these disorders. In this study, a composite nanofibrous scaffold was fabricated from chitosan, collagen, and polyvinyl-alcohol polymer blend while curcumin incorporated in scaffold fibers. The scaffold supportive functions from smooth muscle cell differentiation were studied when human-induced pluripotent stem cells were cultured on the scaffolds under differentiation medium. Biocompatibility of the fabricated scaffold increased significantly by incorporating curcumin in the scaffold fibers, where protein adsorption, cell attachment, and viability were increased in the nanofiber/curcumin group compared with the other groups. In addition, the expression level of smooth muscle cell-related genes, including alpha-smooth muscle actin (αSMA), smooth muscle 22 alpha (SM-22a), Caldesmon1, and Calponin1in the stem cells upregulated while cultured in the presence of curcumin, but this increase was significantly improved while cells cultured on the nanofibers/curcumin. In addition, αSMA protein in the cells cultured on the nanofibers/curcumin expressed significantly higher than those cells cultured on the nanofibers without curcumin. It can be concluded that smooth muscle cell differentiation of the induced pluripotent stem cells promoted by curcumin and this promotion was synergistically improved while curcumin incorporated in the nanofibers. [Figure: see text]
has issue date	2020-04-19(xsd:dateTime)
bibo:doi	10.1007/s11626-020-00445-6
bibo:pmid	32307668
has license	no-cc
sha1sum (hex)	88365d34b4ca4166f628453bc7ef9bd491b6d402
schema:url	https://doi.org/10.1007/s11626-020-00445-6
resource representing a document's title	Efficient smooth muscle cell differentiation of iPS cells on curcumin-incorporated chitosan/collagen/polyvinyl-alcohol nanofibers
has PubMed Central identifier	PMC7223336
has PubMed identifier	32307668
schema:publication	In Vitro Cell Dev Biol Anim
resource representing a document's body	covid:88365d34b4ca4166f628453bc7ef9bd491b6d402#body_text
is schema:about of	named entity 'ADDITION' named entity 'COLLAGEN' named entity 'BIOCOMPATIBILITY' named entity 'POLYVINYL' named entity 'ALPHA-SMOOTH MUSCLE ACTIN' named entity 'STUDY' named entity 'NANOFIBER' named entity 'stem cells' named entity 'curcumin' named entity 'nanofibers' named entity 'curcumin' named entity 'curcumin' named entity 'curcumin' named entity 'nanofibers' named entity 'alcohol' named entity 'smooth muscle cell' named entity 'Tissue engineering' named entity 'smooth muscle' named entity 'nanofiber' named entity 'gene expression' named entity 'nanofibrous scaffolds' named entity 'alcohol' named entity 'adult stem cell' named entity 'iPSCs' named entity 'stem cells' named entity 'primers' named entity 'polymers' named entity 'Shahid Beheshti University of Medical Sciences' named entity 'curcumin' named entity 'PBS' named entity 'curcumin' named entity 'iPSCs' named entity 'iPSCs' named entity 'electrospinning' named entity 'alcohol' named entity 'Wettability' named entity 'star sign' named entity 'regenerative medicine' named entity 'contact angle goniometer' named entity 'biodegradation' named entity 'sterilization' named entity 'PVA' named entity 'tissue engineering' named entity 'chitosan' named entity 'iPSCs' named entity '0.01' named entity 'curcumin' named entity 'glutaraldehyde' named entity 'parts of the body' named entity 'natural polymers' named entity 'smooth muscle cells' named entity 'spectroscopy' named entity 'nanofiber' named entity 'mbar' named entity 'Japan' named entity 'probability' named entity 'SMC' named entity 'non-toxic' named entity 'SMC' named entity 'Darmstadt' named entity 'bovine' named entity 'Winooski' named entity 'solvent' named entity 'PBS' named entity 'polymer' named entity 'antibacterial' named entity 'bladder' named entity 'SPSS' named entity 'curcumin' named entity 'tissue engineering' named entity 'bladder' named entity 'nanofiber' named entity 'star sign' named entity 'genitourinary' named entity 'PBS'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software