About: SARS-CoV-2 detection in setting of viral swab scarcity: are MRSA swabs and viral swabs equivalent?

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About: SARS-CoV-2 detection in setting of viral swab scarcity: are MRSA swabs and viral swabs equivalent? Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	SARS-CoV-2 detection in setting of viral swab scarcity: are MRSA swabs and viral swabs equivalent?
Creator	Campbell, Sheldon Peaper, David Dembry, Louise Federman, Daniel Fisher, Ann Gupta, Shaili Haven, West Kozal, Michael Ruser, Christopher Stack, Gary Tarabar, Asim
Source	MedRxiv
abstract	Abstract: Background: The global pandemic of Severe Acute Respiratory Syndrome-Related Coronavirus 2 (SARS-CoV2) has resulted in unprecedented challenges for healthcare systems. One barrier to widespread testing has been a paucity of traditional respiratory viral swab collection kits relative to the demand. Whether other sample collection kits, such as widely available MRSA nasal swabs can be used to detect SARS-CoV-2 is unknown. Methods: We compared simultaneous nasal MRSA swabs (COPAN ESwabs 480C flocked nasal swab in 1mL of liquid Amies medium) and virals wabs (BD H192(07) flexible mini-tip flocked nasopharyngeal swabs in 3mL Universal Transport Medium) for SARS-CoV-2 PCR testing using Simplexa COVID-19 Direct assay on patients over a 4-day period. When the results were discordant, the viral swab sample was run again on the Cepheid Xpert Xpress SARS-CoV-2 assay. Results: Of the 81 included samples, there were 19 positives and 62 negatives in viral media and 18 positives and 63 negative in the MRSA swabs. Amongst all included samples, there was concordance between the COPAN ESwabs 480C and the viral swabs in 78 (96.3%). Conclusion: We found a high rate of concordance in test results between COPAN ESwabs 480C in Amies solution and BD H192(07) nasopharyngeal swabs in in 3 mL of Universal Viral Transport medium viral media. Clinicians and laboratories should feel better informed and assured using COPAN ESwabs 480C to help in the diagnosis of COVID-19.
has issue date	2020-05-08(xsd:dateTime)
bibo:doi	10.1101/2020.05.04.20084657
has license	medrxiv
sha1sum (hex)	87fb345224ccd23b78643b122bba5b037ed2c5d2
schema:url	https://doi.org/10.1101/2020.05.04.20084657
resource representing a document's title	SARS-CoV-2 detection in setting of viral swab scarcity: are MRSA swabs and viral swabs equivalent?
resource representing a document's body	covid:87fb345224ccd23b78643b122bba5b037ed2c5d2#body_text
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