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About:
Epidemiological and clinical characteristics of discharged patients infected with SARS‐CoV‐2 on the Qinghai plateau
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schema:ScholarlyArticle
, within Data Space :
covidontheweb.inria.fr
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document(s)
Type:
Academic Article
research paper
schema:ScholarlyArticle
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type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
has title
Epidemiological and clinical characteristics of discharged patients infected with SARS‐CoV‐2 on the Qinghai plateau
Creator
Wang, Xiaoyi
Xu, Jian
Ma, Xiaoli
Bai, Huanying
Dai, Jingtao
Ding, Yuehe
Ma, Xiuzhen
Nuermberger, Eric
Shi, Lianmeng
Xi, Aiqi
Zheng, Hongying
Zhuo, Ma
Source
Medline; PMC
abstract
Since the outbreak of coronavirus disease 2019 (COVID‐19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) was first reported in Wuhan, a series of confirmed cases of COVID‐19 were found on the Qinghai‐Tibet plateau. We aimed to describe the epidemiological, clinical characteristics, and outcomes of all confirmed cases in Qinghai, a province at high altitude. The region had no sustained local transmission. Of all 18 patients with confirmed SARS‐CoV‐2 infection, 15 patients comprising 4 transmission clusters were identified. Three patients were infected by direct contact without travel history to Wuhan. Of 18 patients, 10 patients showed bilateral pneumonia and 2 patients showed no abnormalities. Three patients with comorbidities such as hypertension, liver diseases or diabetes developed severe illness. High C‐reactive protein levels and elevations of both ALT and AST were observed in 3 severely ill patients on admission. All 18 patients were eventually discharged, including the 3 severe patients who recovered after treatment with non‐invasive mechanical ventilation, convalescent plasma and other therapies. Our findings confirmed human‐to‐human transmission of SARS‐CoV‐2 in clusters. Patients with comorbidities are more likely to develop severe illness. This article is protected by copyright. All rights reserved.
has issue date
2020-05-21
(
xsd:dateTime
)
bibo:doi
10.1002/jmv.26032
bibo:pmid
32437017
has license
no-cc
sha1sum (hex)
8749b10ffcf9629c9196bec5ec4ed411c898d24d
schema:url
https://doi.org/10.1002/jmv.26032
resource representing a document's title
Epidemiological and clinical characteristics of discharged patients infected with SARS‐CoV‐2 on the Qinghai plateau
has PubMed Central identifier
PMC7280617
has PubMed identifier
32437017
schema:publication
J Med Virol
resource representing a document's body
covid:8749b10ffcf9629c9196bec5ec4ed411c898d24d#body_text
is
schema:about
of
named entity 'transmission'
named entity 'cases'
named entity 'SARS-CoV-2'
named entity 'outbreak'
named entity 'identified'
named entity 'series'
named entity 'infected'
named entity 'local transmission'
named entity 'severe acute respiratory syndrome coronavirus 2'
named entity 'infection'
named entity 'Qinghai'
named entity 'diabetes'
named entity 'ACE2'
named entity 'respiratory failure'
named entity 'IgG'
named entity 'PCR'
named entity 'comorbidities'
named entity 'neutropenia'
named entity 'epidemiological'
named entity 'RNA'
named entity '3000 meters'
named entity 'antibody'
named entity 'CT imaging'
named entity 'pneumonia'
named entity 'SARS-CoV-2'
named entity 'ground glass opacities'
named entity 'reverse-transcriptase'
named entity 'diabetes'
named entity 'April 6'
named entity 'AST'
named entity 'nucleic acid amplification test'
named entity 'pneumonia'
named entity 'epidemiological'
named entity 'Prevention and Control'
named entity 'COVID'
named entity 'Xi'an, China'
named entity 'lung diseases'
named entity 'angiotensin-converting enzyme 2'
named entity 'clinical characteristics'
named entity 'COVID'
named entity 'lungs'
named entity 'convalescent plasma'
named entity 'cough'
named entity 'eosinophilia'
named entity 'hypertension'
named entity 'World Health Organization'
named entity 'viral infection'
named entity 'traditional Chinese medicine'
named entity 'convalescent plasma therapy'
named entity 'polymyositis'
named entity 'Qinghai province'
named entity 'Wuhan'
named entity 'Wuhan'
named entity 'fatigue'
named entity 'COVID'
named entity 'demographic data'
named entity 'fatigue'
named entity 'infection'
named entity 'gene'
named entity 'Wuhan'
named entity 'National Health Commission of the People's Republic of China'
named entity 'Hubei Province'
named entity 'blood vessels'
named entity 'nucleic acid detection'
named entity 'antibacterial'
named entity 'statistically significant'
named entity 'host cells'
named entity 'oxygen'
named entity 'ethics'
named entity 'COVID'
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