About: A rapid immunochromatographic test strip for detecting rabies virus antibody

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	A rapid immunochromatographic test strip for detecting rabies virus antibody
Creator	Wang, Chengyu Xia, Xianzhu Yang, Songtao Zou, Xiaohuan Feng, Na Gao, Yuwei Wang, Hualei Wang, Tiecheng Zheng, Xuexing Hou, Xiaoqiang Huang, Geng Huang, Hainan Su, Jianqing Yang, Ruimei
Source	Elsevier; Medline; PMC
abstract	An immunochromatographic test strip (ICTS) for detecting antibodies to rabies virus was developed, using colloidal gold particles labeled with rabies virus glycoprotein as the tracer. The assay was evaluated using sera from dogs immunized with various commercial rabies vaccines, or from dogs in the clinics and sera from dogs immunized with vaccines against pathogens other than rabies virus, and negative sera from a wide variety of animal sources, including dogs, mice, and cats which had never been vaccinated. The ICTS was found to be highly specific for antibodies against rabies virus, with a detection limit of 0.5 IU/ml as measured by the fluorescent antibody virus neutralization (FAVN) test. Compared with the FAVN test, the specificity and sensitivity of ICTS were 98.2% and 90.4%, respectively. There was an excellent agreement between results obtained by the ICTS and FAVN tests (kappa = 0.888). Strips stored at 4 °C in a plastic bag with a desiccant retained their specificity and sensitivity for at least 15 months, and strips stored at ambient temperature remained stable for 12 months. The immunochromatographic test strip may therefore be useful for clinical laboratories lacking specialized equipment and for diagnosis in the field for rapid detection of rabies virus-specific antibodies.
has issue date	2010-09-15(xsd:dateTime)
bibo:doi	10.1016/j.jviromet.2010.09.002
bibo:pmid	20837065
has license	no-cc
sha1sum (hex)	8656bed5cbc03e462d32fd08ac1c880bd47edffa
schema:url	https://doi.org/10.1016/j.jviromet.2010.09.002
resource representing a document's title	A rapid immunochromatographic test strip for detecting rabies virus antibody
has PubMed Central identifier	PMC7112791
has PubMed identifier	20837065
schema:publication	J Virol Methods
resource representing a document's body	covid:8656bed5cbc03e462d32fd08ac1c880bd47edffa#body_text
is schema:about of	named entity 'animal' named entity 'field' named entity 'rapid' named entity 'antibodies' named entity 'sensitivity' named entity 'virus' named entity 'desiccant' named entity 'labeled' covid:arg/8656bed5cbc03e462d32fd08ac1c880bd47edffa named entity 'antibodies' named entity 'immunochromatographic' named entity 'neutralization' named entity 'specificity' named entity 'rabies' named entity 'dogs' named entity 'sera' named entity 'wide' named entity 'virus' named entity 'Strips' named entity 'evaluated' named entity 'antibody' named entity 'specificity and sensitivity' named entity 'pathogens' named entity 'fluorescent antibody' named entity 'detection limit' named entity 'colloidal gold particles' named entity 'immunochromatographic' named entity 'rabies virus' named entity 'immunochromatographic' named entity 'WHO' named entity 'neutralizing antibody' named entity 'EDTA' named entity 'CVS' named entity 'plastic bag' named entity 'Colloidal gold' named entity 'glycoprotein' named entity 'antigens' named entity 'PBS' named entity 'fiberglass' named entity 'Cliquet' named entity 'centrifugation' named entity 'rabies' named entity 'virus' named entity 'serum samples' named entity 'incubation' named entity 'rabies virus' named entity 'sample pad' named entity 'adhesive' named entity 'sucrose' named entity 'mammalian species' named entity 'centrifugation' named entity 'biocontainment' named entity 'SDS-PAGE' named entity 'Olympus Corporation' named entity 'St. Louis' named entity 'antigen' named entity 'pathogens' named entity 'rabies virus' named entity 'correlation' named entity 'assay' named entity 'antibodies' named entity 'titer' named entity 'Fujirebio' named entity 'centrifugation' named entity 'protein' named entity 'serum' named entity 'serum samples' named entity 'rabies virus'

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