About: Upsurge of Enterovirus D68 and Circulation of the New Subclade D3 and Subclade B3 in Beijing, China, 2016

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About: Upsurge of Enterovirus D68 and Circulation of the New Subclade D3 and Subclade B3 in Beijing, China, 2016 Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Upsurge of Enterovirus D68 and Circulation of the New Subclade D3 and Subclade B3 in Beijing, China, 2016
Creator	Xiang, Zichun Li, Aihua Gong, Cheng Huang, Fang Luo, Ming Zhang, Tiegang Li, Maozhong Shen, Lingyu
Source	Medline; PMC
abstract	We conducted a surveillance among acute respiratory tract infection (ARTI) cases to define the epidemiology, clinical characteristics and genetic variations of enterovirus D68 (EV-D68) in Beijing, China from 2015 to 2017. Nasopharyngeal swabs and sputum were collected from 30 sentinel hospitals in Beijing and subjected to EV and EV-D68 detection by real-time PCR. The VP1 gene region and complete genome sequences of EV-D68 positive cases were analyzed. Of 21816 ARTI cases, 619 (2.84%) were EV positive and 42 cases were EV-D68 positive. The detection rates of EV-D68 were 0 (0/6644) in 2015, 0.53% (40/7522) in 2016 and 0.03% (2/7650) in 2017, respectively. Two peaks of EV-D68 infections occurred in late summer and early-winter. Ten cases (23.81%) with upper respiratory tract infection and 32 cases (76.19%) presented with pneumonia, including 3 cases with severe pneumonia. The phylogenetic analysis suggested 15 subclade D3 strains and 27 subclade B3 strains of EV-D68 were circulated in China from 2016 to 2017. A total of 52 amino acid polymorphisms were identified between subclades D1 and D3. These data suggest an upsurge of EV-D68 occurred in Beijing in 2016, the new subclade D3 emerged in 2016 and co-circulated with subclade B3 between 2016 and 2017.
has issue date	2019-04-15(xsd:dateTime)
bibo:doi	10.1038/s41598-019-42651-7
bibo:pmid	30988475
has license	cc-by
sha1sum (hex)	85544c40199592db3f81823f341f19f303fef7ec
schema:url	https://doi.org/10.1038/s41598-019-42651-7
resource representing a document's title	Upsurge of Enterovirus D68 and Circulation of the New Subclade D3 and Subclade B3 in Beijing, China, 2016
has PubMed Central identifier	PMC6465342
has PubMed identifier	30988475
schema:publication	Sci Rep
resource representing a document's body	covid:85544c40199592db3f81823f341f19f303fef7ec#body_text
is schema:about of	named entity 'CIRCULATION' named entity 'real-time PCR' named entity '2017' named entity 'suggested' named entity 'INFECTIONS' named entity 'DETECTION' named entity 'UPPER RESPIRATORY TRACT INFECTION' named entity 'PRESENTED' named entity 'LATE' named entity 'PEAKS' named entity 'PNEUMONIA' named entity 'PHYLOGENETIC ANALYSIS' named entity 'SEVERE PNEUMONIA' named entity 'ENTEROVIRUS D68' named entity 'EARLY' named entity 'COLLECTED' named entity 'SUGGEST' named entity 'NEW' named entity '0.03' named entity '2015' named entity '282' named entity 'TOTAL' named entity 'IDENTIFIED' named entity 'REAL-TIME PCR' named entity 'CIRCULATED' named entity 'HOSPITALS' named entity 'NEW' named entity 'RATES' named entity 'EV-D68' named entity 'POSITIVE' named entity 'DATA' named entity 'AMINO ACID' named entity 'COMPLETE' named entity 'SENTINEL' named entity 'NASOPHARYNGEAL' named entity 'VP1' named entity 'STRAINS' named entity 'SWABS' named entity 'ANALYZED' named entity 'SEQUENCES' named entity 'ARTI' named entity 'INCLUDING' named entity 'POLYMORPHISMS' named entity 'BEIJING' named entity 'WINTER' named entity 'OPEN' named entity 'BEIJING' named entity 'GENE REGION' named entity 'SUMMER' named entity 'OCCURRED' named entity 'SPUTUM' named entity '21816' named entity 'GENOME' named entity 'CHINA' named entity 'CASES' named entity 'THESE' covid:arg/85544c40199592db3f81823f341f19f303fef7ec named entity 'subclade' named entity 'upper respiratory tract infection' named entity 'pneumonia' named entity 'total' named entity 'subclades' named entity 'emerged' named entity 'sentinel' named entity 'EV-D68' named entity 'Enterovirus D68' named entity 'pneumonia' named entity 'amino acid' named entity 'gene' named entity 'VP1' named entity 'China' named entity 'EV-D68' named entity 'upper respiratory tract infection' named entity 'Beijing'

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