About: Conflicting results have been published on prognostic significance of central venous to arterial PCO(2) difference (∆PCO(2)) after cardiac surgery. We compared the prognostic value of ∆PCO(2) on intensive care unit (ICU) admission to an original algorithm combining ∆PCO(2), ERO(2) and lactate to identify different risk profiles. Additionally, we described the evolution of ∆PCO(2) and its correlations with ERO(2) and lactate during the first postoperative day (POD1). In this monocentre, prospective, and pilot study, 25 patients undergoing conventional cardiac surgery were included. Central venous and arterial blood gases were collected on ICU admission and at 6, 12 and 24 h postoperatively. High ∆PCO(2) (≥ 6 mmHg) on ICU admission was found to be very frequent (64% of patients). Correlations between ∆PCO(2) and ERO(2) or lactate for POD1 values and variations were weak or non-existent. On ICU admission, a high ∆PCO(2) did not predict a prolonged ICU length of stay (LOS). Conversely, a significant increase in both ICU and hospital LOS was observed in high-risk patients identified by the algorithm: 3.5 (3.0–6.3) days versus 7.0 (6.0–8.0) days (p = 0.01) and 12.0 (8.0–15.0) versus 8.0 (8.0–9.0) days (p < 0.01), respectively. An algorithm incorporating ICU admission values of ∆PCO(2), ERO(2) and lactate defined a high-risk profile that predicted prolonged ICU and hospital stays better than ∆PCO(2) alone.   Goto Sponge  NotDistinct  Permalink

An Entity of Type : fabio:Abstract, within Data Space : covidontheweb.inria.fr associated with source document(s)

AttributesValues
type
value
  • Conflicting results have been published on prognostic significance of central venous to arterial PCO(2) difference (∆PCO(2)) after cardiac surgery. We compared the prognostic value of ∆PCO(2) on intensive care unit (ICU) admission to an original algorithm combining ∆PCO(2), ERO(2) and lactate to identify different risk profiles. Additionally, we described the evolution of ∆PCO(2) and its correlations with ERO(2) and lactate during the first postoperative day (POD1). In this monocentre, prospective, and pilot study, 25 patients undergoing conventional cardiac surgery were included. Central venous and arterial blood gases were collected on ICU admission and at 6, 12 and 24 h postoperatively. High ∆PCO(2) (≥ 6 mmHg) on ICU admission was found to be very frequent (64% of patients). Correlations between ∆PCO(2) and ERO(2) or lactate for POD1 values and variations were weak or non-existent. On ICU admission, a high ∆PCO(2) did not predict a prolonged ICU length of stay (LOS). Conversely, a significant increase in both ICU and hospital LOS was observed in high-risk patients identified by the algorithm: 3.5 (3.0–6.3) days versus 7.0 (6.0–8.0) days (p = 0.01) and 12.0 (8.0–15.0) versus 8.0 (8.0–9.0) days (p < 0.01), respectively. An algorithm incorporating ICU admission values of ∆PCO(2), ERO(2) and lactate defined a high-risk profile that predicted prolonged ICU and hospital stays better than ∆PCO(2) alone.
subject
  • Algorithms
  • Intensive care medicine
  • Hospital departments
  • Medical terminology
  • Surgical specialties
  • Mathematical logic
  • Theoretical computer science
  • Diagnostic intensive care medicine
  • Fifth Colvmn Records albums
part of
is abstract of
is hasSource of
Faceted Search & Find service v1.13.91 as of Mar 24 2020


Alternative Linked Data Documents: Sponger | ODE     Content Formats:       RDF       ODATA       Microdata      About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data]
OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software