About: Peroral immunotheraphy with yolk antibodies for the prevention and treatment of enteric infections

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About: Peroral immunotheraphy with yolk antibodies for the prevention and treatment of enteric infections Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Peroral immunotheraphy with yolk antibodies for the prevention and treatment of enteric infections
Creator	Carlander, David Kollberg, Hans Larsson, Anders Wejåker, Per-Erik
Source	Medline; PMC
abstract	Oral administration of specific antibodies is an attractive approach to establish protective immunity against gastrointestinal pathogens in humans and animals. The increasing number of antibiotic-resistant bacteria emphasize the need to find alternatives to antibiotics. Immunotherapy can also be used against pathogens that are difficult to treat with traditional antibiotics. Laying hens are very good producers of specific antibodies. After immunization, the specific antibodies are transported to the egg yolk from which the antibodies then can be purified. A laying hen produces more than 20 g of yolk antibodies (IgY) per year. These antibodies also have biochemical properties that make them attractive for peroral immunotherapy: They neither activate mammalian complement nor interact with mammalian Fc receptors that could mediate inflammatory response in the gastrointestinal tract. Eggs are also normal dietary components and thus there is practically no risk of toxic side effects of IgY. Yolk antibodies have been shown in several studies to prevent bacterial and viral infections.
has issue date	2000-01-01(xsd:dateTime)
bibo:doi	10.1385/ir:21:1:1
bibo:pmid	10803878
has license	no-cc
sha1sum (hex)	83c206ed163d6024781f1b508c3b536721d69d63
schema:url	https://doi.org/10.1385/ir:21:1:1
resource representing a document's title	Peroral immunotheraphy with yolk antibodies for the prevention and treatment of enteric infections
has PubMed Central identifier	PMC7090601
has PubMed identifier	10803878
schema:publication	Immunol Res
resource representing a document's body	covid:83c206ed163d6024781f1b508c3b536721d69d63#body_text
is schema:about of	named entity 'MORE THAN' named entity 'RISK OF' named entity 'ANTIBIOTICS' named entity 'IMMUNOTHERAPY' named entity 'TOXIC' named entity 'BACTERIAL' named entity 'MAKE' named entity 'COMPLEMENT' named entity 'INTERACT' named entity 'ANTIBIOTIC-RESISTANT BACTERIA' named entity 'APPROACH' named entity 'NEED' named entity 'PER YEAR' named entity 'activate' named entity 'studies' named entity 'They' named entity 'emphasize' named entity 'animals' named entity 'pathogens' named entity 'Prevention' named entity 'FC RECEPTORS' named entity 'DIFFICULT' named entity 'HENS' named entity 'ANTIBODIES' named entity 'PREVENTION' named entity 'YOLK' named entity 'NO RISK' named entity 'ATTRACTIVE' named entity 'IMMUNIZATION' named entity 'PATHOGENS' named entity 'GASTROINTESTINAL TRACT' named entity 'PROPERTIES' named entity 'ANIMALS' named entity 'TRADITIONAL' named entity 'HUMANS' named entity 'DIETARY COMPONENTS' named entity 'NEITHER' named entity 'TREATMENT' named entity 'INFECTIONS' named entity 'SIDE EFFECTS' named entity 'ORAL ADMINISTRATION' named entity 'TO PREVENT' named entity 'STUDIES' named entity 'VERY GOOD' named entity 'IGY' named entity 'MAMMALIAN' named entity 'ACTIVATE' named entity 'MEDIATE' named entity 'LAYING' named entity 'PROTECTIVE IMMUNITY' named entity 'NORMAL' named entity 'USED' named entity 'ESTABLISH' named entity 'ENTERIC' named entity 'PRODUCERS' named entity 'LAYING HEN' named entity 'GASTROINTESTINAL PATHOGENS' named entity 'YOLK' named entity 'NUMBER OF' named entity 'HAVE' named entity 'EGGS' named entity 'ANTIBODIES' named entity 'BIOCHEMICAL' named entity 'PURIFIED' named entity 'INCREASING' named entity 'SPECIFIC' named entity 'INFLAMMATORY RESPONSE' named entity 'BACTERIA ' named entity 'VIRAL INFECTIONS' named entity 'THESE' named entity 'TREAT' named entity 'EGG YOLK' covid:arg/83c206ed163d6024781f1b508c3b536721d69d63 named entity 'antibodies' named entity 'complement' named entity 'produces' named entity 'alternatives' named entity 'biochemical'

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