About: Vomiting and wasting disease associated with hemagglutinating encephalomyelitis viruses infection in piglets in jilin, china

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About: Vomiting and wasting disease associated with hemagglutinating encephalomyelitis viruses infection in piglets in jilin, china Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Vomiting and wasting disease associated with hemagglutinating encephalomyelitis viruses infection in piglets in jilin, china
Creator	Chen, Keyan Du, Chongtao Gao, Feng Gao, Wei He, Wenqi Lan, Yungang Lu, Huijun Ren, Wenzhi Song, Deguang Zhao, Kui Zhao, Chuanbo Li, Zhiping Xie, Shengnan
Source	Medline; PMC
abstract	One coronavirus strain was isolated from brain tissues of ten piglets with evident clinical manifestations of vomiting, diarrhea and dyskinesia in Jilin province in China. Antigenic and genomic characterizations of the virus (isolate PHEV-JLsp09) were based on multiplex PCR and negative staining electron microscopy and sequence analysis of the Hemagglutinin-esterase (HE) gene. These piglets were diagnosed with Porcine hemagglutinating encephalomyelitis virus (PHEV). Necropsy was performed on the piglets. Major pathological changes included meningeal hyperemia, meningeal hemorrhage and cortical hemorrhage. Minor changes were also observed in other organs. Histopathological changes included satellitosis and neuronophagia in the cerebral cortex. Mice were infected with the isolated virus. Their histopathological changes were similar to those symptoms observed in the piglets, exhibiting typical changes for non-suppurative encephalitis. Thus, Porcine hemagglutinating encephalomyelitis virus mainly causes damage to the nervous system but also impacts other organs. This viral strain (isolate PHEV-JLsp09) found in the Siping area of Jilin Province in China is evolutionally closest to the HEV-67N stain (North American strain), indicating that this viral strain evolved from the PHEV from North America.
has issue date	2011-03-21(xsd:dateTime)
bibo:doi	10.1186/1743-422x-8-130
bibo:pmid	21418610
has license	cc-by
sha1sum (hex)	828433debf53d822b26035b951ec78a6f3009de1
schema:url	https://doi.org/10.1186/1743-422x-8-130
resource representing a document's title	Vomiting and wasting disease associated with hemagglutinating encephalomyelitis viruses infection in piglets in jilin, china
has PubMed Central identifier	PMC3071789
has PubMed identifier	21418610
schema:publication	Virol J
resource representing a document's body	covid:828433debf53d822b26035b951ec78a6f3009de1#body_text
is schema:about of	named entity 'hemagglutinating' named entity 'evident' named entity 'negative staining' named entity 'ENCEPHALOMYELITIS' named entity 'CLINICAL MANIFESTATIONS' named entity 'CEREBRAL CORTEX' named entity 'OBSERVED' covid:arg/828433debf53d822b26035b951ec78a6f3009de1 named entity 'ASSOCIATED WITH' named entity 'VIRUS' named entity 'JILIN PROVINCE' named entity 'BASED' named entity 'CAUSES' named entity 'CHINA' named entity 'PORCINE HEMAGGLUTINATING ENCEPHALOMYELITIS VIRUS' named entity 'VOMITING' named entity 'VIRUSES INFECTION' named entity 'HYPEREMIA' named entity 'INCLUDED' named entity 'CHANGES' named entity 'ESTERASE' named entity 'HISTOPATHOLOGICAL' named entity 'CHINA' named entity 'DISEASE ASSOCIATED' named entity 'MENINGEAL HEMORRHAGE' named entity 'EXHIBITING' named entity 'DYSKINESIA' named entity 'HEMAGGLUTININ' named entity 'NECROPSY' named entity 'MINOR' named entity 'DIAGNOSED' named entity 'BRAIN TISSUES' named entity 'STRAIN' named entity 'MICE' named entity 'THESE' named entity 'IMPACTS' named entity 'SUPPURATIVE ENCEPHALITIS' named entity 'ISOLATED' named entity 'MULTIPLEX PCR' named entity 'INFECTED' named entity 'NON-' named entity 'CORTICAL HEMORRHAGE' named entity 'PATHOLOGICAL' named entity 'SYMPTOMS' named entity 'GENOMIC' named entity 'ELECTRON MICROSCOPY' named entity 'BUT' named entity 'VOMITING' named entity 'MENINGEAL' named entity 'PERFORMED' named entity 'THEIR' named entity 'DIARRHEA' named entity 'ORGANS' named entity 'SEQUENCE ANALYSIS' named entity 'DAMAGE' named entity 'GENE' named entity 'CORONAVIRUS' named entity 'NERVOUS SYSTEM' named entity 'TYPICAL' named entity 'MAJOR' named entity 'WASTING DISEASE' named entity 'NEGATIVE STAINING' named entity 'NEURONOPHAGIA' named entity 'PHEV' named entity 'SATELLITOSIS' named entity 'SIMILAR' named entity 'Necropsy' named entity 'hemagglutinating' named entity 'observed'

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