About: Isolation of Aspergillus spp. in respiratory samples of patients with COVID‐19 in a Spanish tertiary care hospital

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About: Isolation of Aspergillus spp. in respiratory samples of patients with COVID‐19 in a Spanish tertiary care hospital Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Isolation of Aspergillus spp. in respiratory samples of patients with COVID‐19 in a Spanish tertiary care hospital
Creator	Group, Working Díaz-Pollán B, Falces-Romero, Ruiz-Bastián, M
source	Medline; PMC
abstract	BACKGROUND: Invasive pulmonary aspergillosis (IPA) is a complication of respiratory bacterial and viral infections such as coronavirus disease 2019 (COVID‐19). PATIENTS/METHODS: In University Hospital La Paz (Madrid, Spain), we reviewed the clinical and demographic characteristics of 10 patients with positive severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) PCR and Aspergillus spp. isolate in respiratory samples. We also recovered results of galactomannan tests in serum and/or bronchoalveolar lavage (BAL) samples. RESULTS: Eight male and two female from 51 to 76 years were recovered. They had reported risk factors to develop IPA (hematological malignancies, immunosuppression, diabetes, obesity, intensive care unit stay, among others). Azole susceptible Aspergillus fumigatus was isolated in nine patients and Aspergillus nidulans was isolated in one patient. Only one case was classified as probable aspergillosis, seven cases as putative aspergillosis, and two cases were not classifiable. Eight patients received antifungal treatment. Seven patients died (70%), two are still inpatient due to nosocomial infections and one was discharged referred to another institution. CONCLUSIONS: This clinical entity has high mortality and therefore it should be performed surveillance with early galactomannan tests and cultures in respiratory samples in order to improve the outcome of the patients with this condition.
has issue date	2020-08-04(xsd:dateTime)
bibo:doi	10.1111/myc.13155
bibo:pmid	32749040
has license	no-cc
sha1sum (hex)	81343c63c8592ff89c5fac579461514b8d38310b
schema:url	https://doi.org/10.1111/myc.13155
resource representing a document's title	Isolation of Aspergillus spp. in respiratory samples of patients with COVID‐19 in a Spanish tertiary care hospital
has PubMed Central identifier	PMC7436624
has PubMed identifier	32749040
schema:publication	Mycoses
resource representing a document's body	covid:81343c63c8592ff89c5fac579461514b8d38310b#body_text
is schema:about of	named entity 'COPYRIGHT' named entity 'BACKGROUND' named entity 'INVASIVE PULMONARY ASPERGILLOSIS' named entity 'All rights reserved' named entity 'COVID-19' named entity 'This' named entity 'antifungal agents' named entity 'underlying condition' named entity 'spp' named entity 'A. nidulans' named entity 'COPD' named entity 'Influenza viruses' named entity 'ICU' named entity 'virus' named entity 'Spain' named entity 'IPA' named entity 'galactomannan' named entity 'immunosuppressed' named entity 'Galactomannan' named entity 'infection' named entity 'sputum' named entity 'Aspergillus' named entity 'corticosteroids' named entity 'spp' named entity 'lopinavir/ritonavir' named entity 'ICU' named entity 'cough' named entity 'HLA' named entity 'serum' named entity 'COVID-19' named entity 'Wuhan City' named entity 'transplant recipients' named entity 'obesity' named entity 'aspergillosis' named entity 'Aspergillus fumigatus' named entity 'tertiary care' named entity 'SARS-CoV-2' named entity 'lung tissue' named entity 'PCR' named entity 'SARS-CoV-2' named entity 'IPA' named entity 'Madrid' named entity 'COVID-19' named entity 'virus' named entity 'ankylosing spondylitis' named entity 'spp' named entity 'corticosteroid' named entity 'EORTC' named entity 'hematological diseases' named entity 'aspergillosis' named entity 'COVID-19' named entity 'diabetes' named entity 'COVID' named entity 'golimumab' named entity 'chronic obstructive pulmonary disease' named entity 'PCR' named entity 'COVID' named entity 'mechanical ventilation' named entity 'HIV' named entity 'Fungal infections' named entity 'IPA' named entity 'microbiological' named entity 'serum' named entity 'PCR' named entity 'risk factors' named entity 'PCR' named entity 'radiographs' named entity 'Aspergillus' named entity 'intensive care unit' named entity 'SARS-CoV-2' named entity 'Coronavirus disease 2019' named entity 'dyspnea' named entity 'fever' named entity 'PCR' named entity 'immunosuppression' named entity 'paralysis' named entity 'antifungal' named entity 'viral infection'

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