About: The spleen morphophysiology of fruit bats

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	The spleen morphophysiology of fruit bats
Creator	Andhika, \| Aryani, \| Doktor, Magister Hanadhita, Desrayni Hondo, \| Mayasari, Ika Ni, \| Pendidikan, Penelitian Prawira, Yudha Putu, Luh Rahma, Anisa Satyaningtijas, Sismin Srihadi, \|
Source	Medline; PMC
abstract	Spleen is one of the important lymphoid organs with wide variations of morphological and physiological functions according to species. Morphology and function of the spleen in bats, which are hosts to several viral strains without exhibiting clinical symptoms, remain to be fully elucidated. This study aims to examine the spleen morphology of fruit bats associated with their physiological functions. Spleen histological observations were performed in three fruit bats species: Cynopterus titthaecheilus (n = 9), Rousettus leschenaultii (n = 3) and Pteropus vampyrus (n = 3). The spleens of these fruit bats were surrounded by a thin capsule. Red pulp consisted of splenic cord and wide vascular space filled with blood. Ellipsoids in all three studied species were found numerously and adjacent to one another forming macrophages aggregates. White pulp consisted of periarteriolar lymphoid sheaths (PALS), lymphoid follicles and marginal zone. The lymphoid follicle contained a germinal centre and a tingible body macrophage that might reflect an active immune system. The marginal zone was prominent and well developed. This study reports some differences in spleen structure of fruit bats compared to other bat species previously reported and discusses possible physiological implications of the spleen based on its morphology.
has issue date	2019-04-10(xsd:dateTime)
bibo:doi	10.1111/ahe.12442
bibo:pmid	30968443
has license	no-cc
sha1sum (hex)	80c475cb0ed6be956a539fcc5e406ff03d6a23e9
schema:url	https://doi.org/10.1111/ahe.12442
resource representing a document's title	The spleen morphophysiology of fruit bats
has PubMed Central identifier	PMC7159459
has PubMed identifier	30968443
schema:publication	Anat Histol Embryol
resource representing a document's body	covid:80c475cb0ed6be956a539fcc5e406ff03d6a23e9#body_text
is schema:about of	named entity 'implications' named entity 'morphology' named entity 'fruit bats' named entity 'aims' named entity 'Spleen' named entity 'White pulp' named entity 'fruit bats' named entity 'histology' named entity 'STUDY' named entity 'FRUIT BATS' named entity 'BLOOD' named entity 'PHYSIOLOGICAL' named entity 'PROMINENT' named entity 'EXHIBITING' named entity 'REFLECT' covid:arg/80c475cb0ed6be956a539fcc5e406ff03d6a23e9 named entity 'Spleen' named entity 'hosts' named entity 'prominent' named entity 'function' named entity 'splenic' named entity 'cord' named entity 'lymphoid follicle' named entity 'spleen' named entity 'fruit bats' named entity 'morphology' named entity 'physiological functions' named entity 'histology' named entity 'macrophages' named entity 'tingible body macrophage' named entity 'morphology' named entity 'spleen' named entity 'White pulp' named entity 'clinical symptoms' named entity 'cats, dogs' named entity 'dendritic cells' named entity 'smooth muscle' named entity 'spleen' named entity 'circulating blood' named entity 'foraging' named entity 'mammals' named entity 'rodents' named entity 'fruit bats' named entity 'special function' named entity 'torpor' named entity 'bat' named entity 'clinical symptoms' named entity 'IgG antibody' named entity 'spleen' named entity 'torpor' named entity 'spleen' named entity 'Yinpterochiroptera' named entity 'spleen' named entity 'megakaryocyte' named entity 'Marburg' named entity 'spleen' named entity 'lymphocyte' named entity 'suborder' named entity 'collagen' named entity 'mammals' named entity 'Erythrocytes' named entity 'Fruit bats' named entity 'sheep' named entity 'virus' named entity 'extramedullary haematopoiesis' named entity 'nuclei' named entity 'pteropodid' named entity 'red pulp' named entity 'Red pulp'

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