About: Coping with COVID‐19: ventilator splitting with differential driving pressures using standard hospital equipment

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About: Coping with COVID‐19: ventilator splitting with differential driving pressures using standard hospital equipment Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Coping with COVID‐19: ventilator splitting with differential driving pressures using standard hospital equipment
Creator	Gregory, S Byrne, T Clarke, A Liao, S Stephens, A
Source	Medline; PMC
abstract	The global COVID‐19 pandemic has led to a worldwide shortage of ventilators. This shortage has initiated discussions on how to support multiple patients with a single ventilator (ventilator splitting). Ventilator splitting is incompletely tested, experimental and the effects have not been fully characterised. This study investigated the effect of ventilator splitting on system variables (inspiratory pressure, flow and volume) and the possibility of different ventilation targets for each limb using only standard hospital equipment. Experiments were conducted on two test lungs with different compliances (0.02 l.cmH(2)O(−1) and 0.04 l.cmH(2)O(−1)). The ventilator was used in both pressure and volume control modes and was set to ventilate the low compliance lungs at end‐tidal volumes of 500 ± 20 ml. A flow restrictor apparatus consisting of a Hoffman clamp and tracheal tube was connected in series to the inspiratory limb of the high compliance test lungs and the resistance modified to achieve end‐tidal volumes of 500 ± 20 ml. The restriction apparatus successfully modified the inspiratory pressure, minute ventilation and volume delivered to the high compliance test lungs in both pressure control (27.3–17.8 cmH(2)O, 15.2–8.0 l.min(−1) and 980–499 ml, respectively) and volume control (21.0–16.7 cmH(2)O, 10.7–7.9 l.min(−1) and 659–498 ml, respectively) ventilation modes. Ventilator splitting is not condoned by the authors. However, these experiments demonstrate the capacity to simultaneously ventilate two test lungs of different compliances, and using only standard hospital equipment, modify the delivered pressure, flow and volume in each test lung.
has issue date	2020-04-25(xsd:dateTime)
bibo:doi	10.1111/anae.15078
bibo:pmid	32271942
has license	no-cc
sha1sum (hex)	804264af323810082c1754e9d73b34836b5736d3
schema:url	https://doi.org/10.1111/anae.15078
resource representing a document's title	Coping with COVID‐19: ventilator splitting with differential driving pressures using standard hospital equipment
has PubMed Central identifier	PMC7262199
has PubMed identifier	32271942
schema:publication	Anaesthesia
resource representing a document's body	covid:804264af323810082c1754e9d73b34836b5736d3#body_text
is schema:about of	named entity 'volumes' named entity 'initiated' named entity 'cmH' named entity 'investigated' named entity 'demonstrate' named entity 'splitting' named entity 'AT END' named entity 'VENTILATOR' named entity 'VARIABLES' named entity 'THESE' named entity 'GLOBAL' named entity 'APPARATUS' named entity 'VENTILATORS' named entity '2 O' covid:arg/804264af323810082c1754e9d73b34836b5736d3 named entity 'modified' named entity 'restriction' named entity 'cmH' named entity 'resistance' named entity 'control' named entity 'tested' named entity 'volumes' named entity 'splitting' named entity 'lungs' named entity 'The' named entity 'pressure' named entity '7.9' named entity '10.7' named entity 'ventilator' named entity 'lungs' named entity 'lungs' named entity 'disease burden' named entity 'tracheal tube' named entity 'Ventilators' named entity 'ventilator' named entity 'COVID-19 pandemic' named entity 'flow restrictor' named entity 'ventilator' named entity 'lungs' named entity 'infection' named entity 'severe respiratory failure' named entity 'mechanical ventilation' named entity 'flow restrictor' named entity 'tidal volume' named entity 'Positive end-expiratory pressure' named entity 'peak inspiratory pressure' named entity 'severe acute respiratory syndrome coronavirus 2' named entity 'COVID' named entity 'ventilator' named entity 'ventilator' named entity 'lung' named entity 'tidal volume' named entity 'ventilator' named entity 'lungs' named entity 'flow restrictor' named entity '10.7' named entity 'airway' named entity 'medical equipment' named entity 'global pandemic' named entity 'lungs' named entity 'SARS-CoV-2' named entity 'ventilator' named entity 'lungs' named entity 'tidal volume' named entity 'ventilator' named entity 'COVID' named entity 'ventilator' named entity 'ventilator' named entity 'medical equipment' named entity 'ventilator' named entity 'ventilator' named entity 'gas exchange' named entity 'flow sensor' named entity 'ventilator' named entity 'minute ventilation' named entity 'virus' named entity 'flow restrictor'

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