About: Surfactant therapy in preterm infants with respiratory distress syndrome and in near-term or term newborns with acute RDS

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About: Surfactant therapy in preterm infants with respiratory distress syndrome and in near-term or term newborns with acute RDS Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Surfactant therapy in preterm infants with respiratory distress syndrome and in near-term or term newborns with acute RDS
Creator	Ramanathan, R
Source	PMC
abstract	Many different surfactant preparations derived from animal sources, as well as synthetic surfactants, are available for the treatment of preterm infants with respiratory distress syndrome (RDS). Natural, modified surfactants containing surfactant-associated proteins appear to be more effective than non-protein-containing synthetic surfactants. Comparative trials with poractant alfa at a higher initial dose of 200 mg/kg appear to be associated with rapid weaning of FiO(2), less need for additional doses, and decreased mortality in infants <32 weeks gestation when compared with beractant. Early rescue (<30 min of age) surfactant therapy is an effective method to minimize over treatment of some preterm infants who may not develop RDS. Surfactant therapy followed by rapid extubation to nasal ventilation appears to be more beneficial than continued mechanical ventilation. In near-term or term newborns with acute RDS, surfactant therapy has been shown to be 70% effective in improving respiratory failure.
has issue date	2006-04-25(xsd:dateTime)
bibo:doi	10.1038/sj.jp.7211474
bibo:pmid	16625226
has license	no-cc
sha1sum (hex)	7f72daa7ea8247828e5f608b0f14f61b5d0b64f1
schema:url	https://doi.org/10.1038/sj.jp.7211474
resource representing a document's title	Surfactant therapy in preterm infants with respiratory distress syndrome and in near-term or term newborns with acute RDS
has PubMed Central identifier	PMC7104450
has PubMed identifier	16625226
schema:publication	J Perinatol
resource representing a document's body	covid:7f72daa7ea8247828e5f608b0f14f61b5d0b64f1#body_text
is schema:about of	named entity 'higher' named entity 'dose' named entity 'newborns' named entity 'NASAL' named entity 'NEAR' named entity 'RESPIRATORY FAILURE' named entity 'MODIFIED' named entity 'INFANTS' named entity 'RDS' named entity 'effective' named entity 'weaning' named entity 'continued' named entity 'age' named entity 'infants' named entity 'beractant' named entity 'gestation' named entity 'RDS' named entity 'RDS' named entity 'surfactant therapy' named entity 'protein' named entity 'respiratory distress syndrome' named entity 'extubation' named entity 'mechanical ventilation' named entity 'Surfactant therapy' named entity 'phosphatidyl choline' named entity 'neonatal intensive care units' named entity 'pneumonia' named entity 'Newborns' named entity 'preterm infants' named entity 'Lotze' named entity 'type II pneumocytes' named entity 'meta-analysis' named entity 'morbidity' named entity 'surfactant' named entity 'respiratory distress syndrome' named entity 'calfactant' named entity 'Warrington, PA' named entity 'surfactants' named entity 'mechanical ventilation' named entity 'beractant' named entity 'mechanical ventilation' named entity 'intubation' named entity 'extremely low birth weight' named entity 'surfactant' named entity 'CDH' named entity 'surfactants' named entity 'surfactant therapy' named entity 'beractant' named entity 'ECMO' named entity 'United States' named entity 'surfactant therapy' named entity 'ARDS' named entity 'congenital' named entity 'preterm infants' named entity 'lung' named entity 'beractant' named entity 'acute phase' named entity 'respiratory distress syndrome' named entity 'gas exchange' named entity 'lucinactant' named entity 'edema' named entity 'surfactants' named entity 'gestation' named entity 'beractant' named entity 'ARDS' named entity 'gestation' named entity 'ARDS' named entity 'Surfactant therapy' named entity 'MAS' named entity 'beractant' named entity 'surfactants' named entity 'duration of action' named entity 'preterm infants' named entity 'surfactant therapy' named entity 'ARDS' named entity 'MAS' named entity 'RDS' named entity 'extubation' named entity 'physiological' named entity 'surfactant' named entity 'congenital diaphragmatic hernia'

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