About: An effective COVID-19 response in South America: the Uruguayan Conundrum

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	An effective COVID-19 response in South America: the Uruguayan Conundrum
Creator	Moratorio, Gonzalo Greif, Gonzalo Aldunate, Fabián Moreno, Pilar Iraola, Gregorio Abin, Andrés Alegretti, Miguel Arim, Ec Badano, José Barbeito, Batthyány, Bidegain, Estela Bonnecarrere, Bresque, Mariana Brito, Gustavo Cohen, Henry Colina, Costábile, Alicia Cristina, Cruces, María Durán, Rosario Díaz-Viraqué, Florencia Ehrlich, Ricardo Fabregat, Matías Fajardo, Álvaro Fernández, Cecilia Ferrés, Ignacio Francia, María Gagliano, Gustavo Henderson, Eduardo López-Tort, Fernando Maidana, Matías Marin, Mónica Nabón, Adriana Paganini, Fernando Perbolianachis, Paula Pereira-Gómez, Marianoel Piattoni, Vanesa Pritsch, Otto Radi, Rivera, Robello, Carlos Rodríguez-Duarte, Jorge Rosa, Raquel Salazar, Cecilia Scavone, Paola Sierra, Simón, Diego Zarantonelli, Leticia
source	MedRxiv
abstract	Background: South America has become the new epicenter of the COVID-19 pandemic with more than 1.1M reported cases and >50,000 deaths (June 2020). Conversely, Uruguay stands out as an outlier managing this health crisis with remarkable success. Methods: We developed a molecular diagnostic test to detect SARS-CoV-2. This methodology was transferred to research institutes, public hospitals and academic laboratories all around the country, creating a COVID-19 diagnostic lab network. Uruguay also implemented active epidemiological surveillance following the Test, Trace and Isolate (TETRIS) strategy coupled to real-time genomic epidemiology. Results: Three months after the first cases were detected, the number of positive individuals reached 826 (23 deaths, 112 active cases and 691 recovered). The Uruguayan strategy was based in a close synergy established between the national health authorities and the scientific community. In turn, academia rapidly responded to develop national RT-qPCR tests. Consequently, Uruguay was able to perform ~1,000 molecular tests per day in a matter of weeks. The COVID-19 diagnostic lab network performed more than 54% of the molecular tests in the country. This, together with real-time genomics, were instrumental to implement the TETRIS strategy, helping to contain domestic transmission of the main outbreaks registered so far. Conclusions: Uruguay has successfully navigated the first trimester of the COVID-19 health crisis in South America. A rapid response by the scientific community to increase testing capacity, together with national health authorities seeking out the support from the academia were fundamental to successfully contain, until now, the COVID-19 outbreak in the country.
has issue date	2020-07-27(xsd:dateTime)
bibo:doi	10.1101/2020.07.24.20161802
has license	medrxiv
sha1sum (hex)	7e6eb9d2050d3d0b652771ee6bc1e2a1f678ae75
schema:url	https://doi.org/10.1101/2020.07.24.20161802
resource representing a document's title	An effective COVID-19 response in South America: the Uruguayan Conundrum
resource representing a document's body	covid:7e6eb9d2050d3d0b652771ee6bc1e2a1f678ae75#body_text
is schema:about of	named entity 'response' named entity 'South America' named entity 'universal access' named entity 'local transmission' named entity 'Uruguay' named entity 'Institut Pasteur' named entity 'preprint' named entity 'SARS-CoV-2' named entity 'World Health Organization' named entity 'Thermo Fisher' named entity 'ICU beds' named entity 'SARS-CoV-2' named entity 'preprint' named entity 'March 13th' named entity 'spike protein' named entity 'T7 RNA polymerase' named entity 'QIAgen' named entity 'SARS-CoV-2' named entity 'ICUs' named entity 'Ministry of Public Health' named entity 'COVID-19' named entity 'mortality rates' named entity 'preprint' named entity 'Uruguay' named entity 'serial dilution' named entity 'July 27' named entity 'Uruguay' named entity 'preprint' named entity 'local transmission' named entity 'SARS-CoV-2' named entity 'Uruguay' named entity 'Uruguay' named entity 'COVID-19' named entity 'Uruguay' named entity 'SARS-CoV-2' named entity 'Austria' named entity 'epidemiological'

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