About: Pulmones azules en pacientes COVID-19: un paso más allá del diagnóstico de tromboembolismo pulmonar mediante TCMD con mapa de yodo

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About: Pulmones azules en pacientes COVID-19: un paso más allá del diagnóstico de tromboembolismo pulmonar mediante TCMD con mapa de yodo Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Pulmones azules en pacientes COVID-19: un paso más allá del diagnóstico de tromboembolismo pulmonar mediante TCMD con mapa de yodo
Creator	Teresa, Maria Prieto, Ramírez Díez, Laura Krauel, Allona María, Dueñas Pérez, Virginia Rojas, Emilio Torres Sánchez, Isabel Ulpiano López De La Guardia, Izquierdo
Source	Elsevier
abstract	Objetivo: evaluar la capacidad diagnóstica de la angiografía pulmonar con tomografía computarizada multidetector (TCMD) y mapa de yodo en el diagnóstico del tromboembolismo pulmonar (TEP), en pacientes con enfermedad por coronavirus COVID-19. Métodos: estudio observacional retrospectivo sobre 81 pacientes consecutivos ingresados con infección respiratoria por COVID-19, a los que se realizó TCMD ante la sospecha clínica de TEP (disnea súbita, dolor torácico, hemoptisis, insuficiencia respiratoria grave (IRG) que no corrige con flujo elevado de O2) y/o elevación del D-dímero. Resultados: de los 81 pacientes estudiados, 64(79,01%) varones, identificamos TEP agudo en 22(27,16%), en 13(59,09%) bilateral y en 13(59,09%) con áreas de hipoperfusión. De los 59(72,83%) pacientes sin TEP en 41(69,49%) se observó hipoperfusión (en un caso atribuible a enfisema pulmonar). En 18(22,2%) del total de pacientes no se vio ni TEP ni hipoperfusión. El patrón “crazy paving” es un factor de riesgo para desarrollar TEP (OR1,94; IC95% 0,28-13,57), así como los patrones “consolidaciones” (OR 1,44; IC95% 0,24-8,48) y “engrosamiento septos/bronquiectasias” (OR 1,47; IC95% 0,12-17,81). Los pacientes con IRG refractaria al O2 mostraron un riesgo 6,36 veces superior para el hallazgo de hipoperfusión en el mapa de yodo. Conclusión: la angiografía pulmonar con TCMD y mapa de yodo, al añadir la imagen funcional a la anatómica, es capaz de demostrar, además del TEP en arterias principales, lobares y segmentarias, la presencia de hipoperfusión en vasos distales, lo cual la convierte en una herramienta de gran utilidad para la adecuada orientación diagnóstica y terapéutica de los pacientes con afectación pulmonar por COVID-19. Objective: To evaluate the diagnostic capacity of pulmonary angiography with multidetector computed tomography (MDCT) and iodine mapping in the diagnosis of pulmonary thromboembolism (PTE) in patients with Covid-19 disease. Methods: Retrospective observational study of 81 consecutive patients admitted with Covid-19 respiratory infection who underwent MDCT for clinical suspicion of PTE (sudden dyspnea, chest pain, hemoptysis, severe respiratory failure (SRF) not corrected with high O2 flow) and/or raised D-dimer. Results: Of the 81 patients studied [64 (79.01%) men], acute PTE was identified in 22 (27.16%), bilaterally in 13 (59.09%), and 13 (59,09%) showed areas of hypoperfusion. Of the 59 (72.83%) patients without PTE, hypoperfusion was observed in 41 (69.49%) (attributable in one case to pulmonary emphysema). In 18 (22.2%) of the total number of patients, neither PTE nor hypoperfusion were seen. A crazy paving pattern is a risk factor for developing PTE (OR 1.94; 95% CI 0.28-13.57), as are consolidations (OR 1.44; 95% CI 0.24-8.48) and septal thickening/bronchiectasis (OR 1.47; 95% CI 0.12-17.81). Patients with O2-refractory SRF showed a 6.36-fold higher risk for hypoperfusion on the iodine map. Conclusion: By adding the functional image to the anatomical image, pulmonary angiography with MDCT and iodine mapping can demonstrate not only PTE in main, lobar and segmental arteries, but also the presence of hypoperfusion in distal vessels. This makes it a highly useful tool for the accurate diagnosis and therapeutic orientation of patients with Covid-19 lung involvement.
has issue date	2020-08-28(xsd:dateTime)
bibo:doi	10.1016/j.arbres.2020.07.031
has license	els-covid
sha1sum (hex)	7d2995cd82ab75e01dc70b5ae2c3912cd65c11ee
schema:url	https://doi.org/10.1016/j.arbres.2020.07.031
resource representing a document's title	Pulmones azules en pacientes COVID-19: un paso más allá del diagnóstico de tromboembolismo pulmonar mediante TCMD con mapa de yodo
resource representing a document's body	covid:7d2995cd82ab75e01dc70b5ae2c3912cd65c11ee#body_text
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