About: Why estimating population-based case fatality rates during epidemics may be misleading

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Why estimating population-based case fatality rates during epidemics may be misleading
Creator	Böttcher, Lucas Chou, Tom Xia, Mingtao
topic	covid:7ccfcb3cbd01edbc3571b84ca191232cbd87318b#this
Source	MedRxiv; Medline; PMC
abstract	Different ways of calculating mortality ratios during epidemics can yield widely different results, particularly during the COVID-19 pandemic. We formulate both a survival probability model and an associated infection duration-dependent SIR model to define individual- and population-based estimates of dynamic mortality ratios. The key parameters that affect the dynamics of the different mortality estimates are the incubation period and the length of time individuals were infected before confirmation of infection. We stress that none of these ratios are accurately represented by the often misinterpreted case fatality ratio (CFR), the number of deaths to date divided by the total number of infected cases to date. Using available data on the recent SARS-CoV-2 outbreaks and simple assumptions, we estimate and compare the different dynamic mortality ratios and highlight their differences. Informed by our modeling, we propose a more systematic method to determine mortality ratios during epidemic outbreaks and discuss sensitivity to confounding effects and errors in the data.
has issue date	2020-03-30(xsd:dateTime)
bibo:doi	10.1101/2020.03.26.20044693
bibo:pmid	32511575
has license	cc-by-nc-nd
sha1sum (hex)	7ccfcb3cbd01edbc3571b84ca191232cbd87318b
schema:url	https://doi.org/10.1101/2020.03.26.20044693
resource representing a document's title	Why estimating population-based case fatality rates during epidemics may be misleading
has PubMed Central identifier	PMC7276002
has PubMed identifier	32511575
schema:publication	medRxiv
resource representing a document's body	covid:7ccfcb3cbd01edbc3571b84ca191232cbd87318b#body_text
is http://vocab.deri.ie/void#inDataset of	proxy:http/ns.inria.fr/covid19/7ccfcb3cbd01edbc3571b84ca191232cbd87318b
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