About: Performance of diagnostic tests to detect respiratory viruses in older adults

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About: Performance of diagnostic tests to detect respiratory viruses in older adults Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Performance of diagnostic tests to detect respiratory viruses in older adults
Creator	Hymas, Weston Schmader, Kenneth Woods, Christopher Polage, Christopher Caram, Lauren Petti, Cathy She, Rosemary Taggart, Edward
Source	Elsevier; Medline; PMC
abstract	Abstract The performance of 4 laboratory methods for diagnosis of viral respiratory tract infections (RTI) in older adults was evaluated. Seventy-four nasopharyngeal (NP) swab specimens were obtained from 60 patients with RTI at a long-term care facility over 2 respiratory seasons. Sixteen specimens were positive for a respiratory virus by at least 1 method. Multiplex reverse transcriptase polymerase chain reaction (RT-PCR) by the Luminex xTAG® Respiratory Viral Panel (RVP) detected 16 (100%) of the positive specimens, RVP of 24-h culture supernatant detected 8 (50%), direct fluorescent antibody testing detected 4 (25%), rapid culture detected 2 (12.5%), and rapid antigen testing detected none. For a comparison group, RVP was performed on NP swabs from 20 outpatient children with RTI. The mean fluorescence intensity by RVP was significantly lower for positive adult patients than pediatric patients (P = 0.0373). Our data suggest that older adult patients shed lower titers of viruses, necessitating a highly sensitive assay such as RT-PCR to reliably detect respiratory viral pathogens.
has issue date	2010-07-31(xsd:dateTime)
bibo:doi	10.1016/j.diagmicrobio.2010.02.020
bibo:pmid	20542205
has license	els-covid
sha1sum (hex)	7ca83352fc240f01245916c96d48cff73214d568
schema:url	https://doi.org/10.1016/j.diagmicrobio.2010.02.020
resource representing a document's title	Performance of diagnostic tests to detect respiratory viruses in older adults
has PubMed Central identifier	PMC7132674
has PubMed identifier	20542205
schema:publication	Diagnostic Microbiology and Infectious Disease
resource representing a document's body	covid:7ca83352fc240f01245916c96d48cff73214d568#body_text
is schema:about of	named entity 'sensitive' named entity 'RVP' named entity 'patients' named entity 'data' named entity 'performed' named entity 'viruses' named entity 'SWABS' named entity 'PEDIATRIC' named entity 'OUR' named entity 'RESPIRATORY TRACT INFECTIONS' named entity 'DIRECT' named entity 'RESPIRATORY' named entity 'ANTIBODY TESTING' named entity 'POSITIVE FOR' named entity 'NASOPHARYNGEAL' named entity 'PATIENTS' named entity 'RT-PCR' named entity 'ASSAY' named entity 'VIRUSES' named entity 'DATA' named entity 'ADULT' named entity 'EVALUATED' named entity 'COMPARISON' named entity 'PERFORMANCE' named entity 'FLUORESCENT ANTIBODY' named entity 'OLDER ADULT' named entity 'CULTURE' named entity 'RESPIRATORY VIRUSES' named entity 'SUGGEST' named entity 'RESPIRATORY VIRUS' named entity 'PERFORMED' named entity 'DIAGNOSTIC TESTS' named entity 'TO DETECT' named entity 'RTI' named entity 'LOWER' named entity 'SIXTEEN' named entity 'SWAB' named entity 'PERFORMANCE' named entity 'VIRAL PATHOGENS' named entity 'CHILDREN' named entity 'OUTPATIENT' named entity 'ANTIGEN TESTING' named entity 'SEASONS' named entity 'LONG-TERM CARE FACILITY' named entity 'MULTIPLEX' named entity '28P' named entity 'SPECIMENS' named entity 'PCR' named entity 'VIRAL' named entity 'POSITIVE' named entity 'REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION' named entity 'CULTURE SUPERNATANT' named entity 'METHOD' named entity 'DETECT' named entity 'RAPID' named entity 'FOR DIAGNOSIS' named entity 'OBTAINED' named entity '28100' named entity 'GROUP' named entity 'RESPIRATORY VIRAL PANEL' named entity 'DETECTED' named entity 'HIGHLY SENSITIVE' named entity 'MEAN FLUORESCENCE INTENSITY' named entity 'LUMINEX' named entity 'LABORATORY METHODS' named entity 'RVP' covid:arg/7ca83352fc240f01245916c96d48cff73214d568 named entity 'detected' named entity 'specimens' named entity 'fluorescent antibody testing' named entity 'RTI' named entity 'direct fluorescent antibody' named entity 'older adult' named entity 'patients'

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