About: Subviral Particle as Vaccine and Vaccine Platform

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Subviral Particle as Vaccine and Vaccine Platform
Creator	Jiang, Xi Tan, Ming
topic	covid:7bbc1ea49a5caefdf52953d806743e90d6c8c4fd#this
Source	Elsevier; Medline; PMC
abstract	Recombinant subvirual particles retain similar antigenic features of their authentic viral capsids and thus have been applied as nonreplicating subunit vaccines against viral infection and illness. Additionally, the self-assembled, polyvalent subviral particles are excellent platforms to display foreign antigens for immune enhancement for vaccine development. These subviral particle-based vaccines are noninfectious and thus safer than the conventional live attenuated and inactivated vaccines. While several VLP vaccines are available in the markets, numerous others, including dual vaccines against more than one pathogen, are under clinical or preclinical development. This article provides an update of these efforts.
has issue date	2014-06-01(xsd:dateTime)
bibo:doi	10.1016/j.coviro.2014.02.009
bibo:pmid	24662314
has license	green-oa
sha1sum (hex)	7bbc1ea49a5caefdf52953d806743e90d6c8c4fd
schema:url	https://doi.org/10.1016/j.coviro.2014.02.009
resource representing a document's title	Subviral Particle as Vaccine and Vaccine Platform
has PubMed Central identifier	PMC4072748
has PubMed identifier	24662314
schema:publication	Current Opinion in Virology
resource representing a document's body	covid:7bbc1ea49a5caefdf52953d806743e90d6c8c4fd#body_text
is http://vocab.deri.ie/void#inDataset of	proxy:http/ns.inria.fr/covid19/7bbc1ea49a5caefdf52953d806743e90d6c8c4fd
is schema:about of	named entity 'PATHOGEN' named entity 'UPDATE' named entity 'HAVE' named entity 'THESE' named entity 'DEVELOPMENT' named entity 'VLP' named entity 'ATTENUATED' named entity 'SUBUNIT VACCINES' named entity 'EXCELLENT' named entity 'APPLIED' named entity 'CONVENTIONAL' named entity 'FOREIGN' named entity 'DUAL' named entity 'ENHANCEMENT' named entity 'ANTIGENS' named entity 'MARKETS' named entity 'INCLUDING' named entity 'PLATFORM' named entity 'VACCINE' named entity 'IMMUNE' named entity 'PARTICLE' named entity 'NUMEROUS' named entity 'SUBVIRAL PARTICLES' named entity 'PROVIDES' named entity 'VIRAL' named entity 'RETAIN' named entity 'FEATURES' named entity 'NONINFECTIOUS' named entity 'SIMILAR' named entity 'PRECLINICAL' named entity 'AVAILABLE' named entity 'ILLNESS' named entity 'TO DISPLAY' named entity 'VACCINES' named entity 'CAPSIDS' named entity 'BASED' named entity 'PARTICLE' named entity 'THEIR' named entity 'ARTICLE' named entity 'INACTIVATED VACCINES' named entity 'VACCINE DEVELOPMENT' named entity 'RECOMBINANT' named entity 'SELF' named entity 'CLINICAL' named entity 'MORE THAN ONE' named entity 'PARTICLES' named entity 'VIRAL INFECTION' named entity 'LIVE' covid:arg/7bbc1ea49a5caefdf52953d806743e90d6c8c4fd named entity 'self-assembled' named entity 'preclinical development' named entity 'live attenuated' named entity 'chimeric vaccine' named entity 'VLPs' named entity 'yeast' named entity 'human trial' named entity 'VLP' named entity 'viral genome' named entity 'heterologous' named entity 'vaccine' named entity 'HBV' named entity 'hepatitis B virus' named entity 'viral pathogens' named entity 'E. coli' named entity 'subviral particles' named entity 'infection' named entity 'immunogenicity' named entity 'viral pathogens' named entity 'chimeric vaccine' named entity 'vaccine' named entity 'chimeric' named entity 'rotavirus' named entity 'vaccine' named entity 'epitope' named entity 'preclinical development' named entity 'London' named entity 'kDa' named entity 'Boehringer Ingelheim'

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