About: Micro and nanoscale technologies in oral drug delivery

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Micro and nanoscale technologies in oral drug delivery Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Micro and nanoscale technologies in oral drug delivery
Creator	Khademhosseini, Ali Stevens, Molly Dokmeci, Mehmet Desai, Tejal Hosseini, Vahid Ahadian, Samad Davoodi, Elham Desai, Diltemiz, Sibel Dokmeci, Remzi Edu, Tejal Fetah, Kirsten Finbloom, Joel Mofidfar, Mohammad Montazerian, Hossein Mylonaki, Ioanna Nasiri, Rohollah Nasrollahi, Fatemeh Org, Khademh@terasaki Sangabathuni, Sivakoti Stevens@imperial, Uk, Tejal
Source	Elsevier; Medline; PMC
abstract	Oral administration is a pillar of the pharmaceutical industry and yet it remains challenging to administer hydrophilic therapeutics by the oral route. Smart and controlled oral drug delivery could bypass the physiological barriers that limit the oral delivery of these therapeutics. Micro- and nanoscale technologies, with an unprecedented ability to create, control, and measure micro- or nanoenvironments, have found tremendous applications in biology and medicine. In particular, significant advances have been made in using these technologies for oral drug delivery. In this review, we briefly describe biological barriers to oral drug delivery and micro and nanoscale fabrication technologies. Micro and nanoscale drug carriers fabricated using these technologies, including bioadhesives, microparticles, micropatches, and nanoparticles, are described. Other applications of micro and nanoscale technologies are discussed, including the fabrication of devices and tissue engineering models to precisely control or assess oral drug delivery in vivo and in vitro, respectively. Strategies to advance translation of micro and nanotechnologies into clinical trials for oral drug delivery are mentioned. Finally, challenges and future prospects on further integration of micro and nanoscale technologies with oral drug delivery systems are highlighted.
has issue date	2020-07-22(xsd:dateTime)
bibo:doi	10.1016/j.addr.2020.07.012
bibo:pmid	32707147
has license	no-cc
sha1sum (hex)	7a9556ae6201881a9ccd7f3b8af5b940e54fb3f7
schema:url	https://doi.org/10.1016/j.addr.2020.07.012
resource representing a document's title	Micro and nanoscale technologies in oral drug delivery
has PubMed Central identifier	PMC7374157
has PubMed identifier	32707147
schema:publication	Adv Drug Deliv Rev
resource representing a document's body	covid:7a9556ae6201881a9ccd7f3b8af5b940e54fb3f7#body_text
is schema:about of	named entity 'Micro' named entity 'https' named entity 'Micro' named entity 'Journal' named entity 'Advanced Drug Delivery Reviews' named entity 'Gelatin' named entity 'lectin' named entity 'microparticles' named entity 'Insulin' named entity 'polymeric materials' named entity 'small intestine' named entity 'nanoparticles' named entity 'patient compliance' named entity 'Ammonium bicarbonate' named entity 'physiological' named entity 'chitosan' named entity 'drug delivery' named entity 'preclinical' named entity 'molecule' named entity 'microparticles' named entity 'bioavailability' named entity 'Nanoparticles' named entity 'intestinal permeability' named entity 'hydrophilic' named entity 'VEGF' named entity 'glucagon-like peptide-1' named entity 'PLGA' named entity 'PLGA' named entity 'secretion' named entity 'Carboxymethyl cellulose' named entity 'microencapsulation' named entity 'pharmacokinetic profile' named entity 'multiple drugs' named entity 'controlled release' named entity 'free radical' named entity 'polymers' named entity 'conjugated' named entity 'hydrophobic' named entity 'PLGA' named entity 'micelle' named entity 'gastric emptying' named entity 'mucus layer' named entity 'Caco-2' named entity 'epithelium' named entity 'electrospinning' named entity 'surfactant' named entity 'electrospinning' named entity 'nanometers' named entity 'P-gp' named entity 'hydrophobic' named entity 'GI tract' named entity 'hydrophobic' named entity 'Methylcellulose' named entity 'photon' named entity 'polyethylene glycol' named entity 'surface area' named entity 'electrostatic interactions' named entity 'microfabrication' named entity 'residence time' named entity 'ammonium nitrate'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software