About: Viral infections associated with Kawasaki disease

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Viral infections associated with Kawasaki disease
Creator	Huang, Li-Min Lin, Ming-Tai Wu, Mei-Hwan Lee, Ping-Ing Chang, Chien-Chih Chang, Luan-Yin Cheng, Ai-Ling Chiang, Bor-Luen Fan, Tsui-Yien Hu, Jen-Jan Lee, Wan-Ling Lu, Chun-Yi Shao, Pei-Lan Yeh, Shu-Jen
Source	Elsevier; Medline; PMC
abstract	Background/Purpose Kawasaki disease (KD) is a disease of unknown cause. To investigate the infectious etiology of Kawasaki disease, we initiated a prospective case-control study to investigate possible links between common viral infections and Kawasaki disease. Methods We enrolled 226 children with KD and 226 age- and sex-matched healthy children from February 2004 to March 2010. Throat and nasopharyngeal swabs were taken for both viral isolation and polymerase chain reaction (PCR) for various viruses. Results The mean age of the 226 KD cases was 2.07 years, and the male to female ratio was 1.43 (133 boys to 93 girls). Their mean fever duration was 7.5 days with a mean peak temperature of 39.7°C. In addition to the typical symptoms of fever, neck lymphadenopathy, lip fissure and/or strawberry tongue, skin rash, nonpurulent bulbar conjunctivitis, palm/sole erythema, and induration followed by periungual desquamation, these KD cases also exhibited cough (69%), rhinorrhea (58%), and diarrhea (45%). Cases of KD had a significantly higher positive rate of viral isolation in comparison with the control group (7.5% vs. 2.2%, p = 0.02). Compared with the control group, cases of KD were more likely to have overall positive rates of viral PCR (50.4% vs. 16.4%, p < 0.001) and for various viruses including enterovirus (16.8% vs. 4.4%, p < 0.001), adenovirus (8.0% vs. 1.8%, p = 0.007), human rhinovirus (26.5% vs. 9.7%, p < 0.001), and coronavirus (7.1% vs. 0.9%, p = 0.003). Conclusion We found that some common respiratory viruses, such as adenoviruses, enteroviruses, rhinoviruses, and coronaviruses, were associated with KD cases.
has issue date	2014-03-31(xsd:dateTime)
bibo:doi	10.1016/j.jfma.2013.12.008
bibo:pmid	24495555
has license	els-covid
sha1sum (hex)	7a4133bebb0d2e668e7f1ee23a1b2e1f3470ebf7
schema:url	https://doi.org/10.1016/j.jfma.2013.12.008
resource representing a document's title	Viral infections associated with Kawasaki disease
has PubMed Central identifier	PMC7125523
has PubMed identifier	24495555
schema:publication	Journal of the Formosan Medical Association
resource representing a document's body	covid:7a4133bebb0d2e668e7f1ee23a1b2e1f3470ebf7#body_text
is schema:about of	named entity 'VIRAL INFECTIONS' covid:arg/7a4133bebb0d2e668e7f1ee23a1b2e1f3470ebf7 named entity 'KAWASAKI DISEASE' named entity 'ASSOCIATED WITH' named entity 'KEYWORDS' named entity 'young children' named entity 'adenovirus' named entity 'clinical features' named entity 'Europe' named entity 'serotyping' named entity 'viruses' named entity 'induration' named entity 'systemic inflammation' named entity 'fever' named entity 'infectious agents' named entity 'indirect fluorescent antibody staining' named entity 'statistically significant' named entity 'Antwerp' named entity 'viruses' named entity 'coronary artery aneurysm' named entity 'primers' named entity 'periungual' named entity 'enterovirus' named entity 'enterovirus infection' named entity 'influenza' named entity 'age distribution' named entity 'intravenous immunoglobulin' named entity 'cough' named entity 'incidence rates' named entity 'Clinical laboratory' named entity 'viral titer' named entity 'fever' named entity 'echogenicity' named entity 'New Haven' named entity 'age distribution' named entity 'echovirus' named entity 'National Taiwan University Hospital' named entity 'etiology' named entity 'echocardiography' named entity 'Japan' named entity 'Kawasaki disease' named entity 'erythema' named entity 'serotype' named entity 'fever' named entity 'cough' named entity 'coronavirus' named entity 'febrile illness' named entity 'respiratory syncytial virus' named entity 'developed world' named entity 'adenoviruses' named entity 'fever' named entity 'respiratory infection' named entity 'questionnaire' named entity 'nasopharyngeal swabs' named entity 'PCR' named entity 'lymphadenopathy' named entity 'febrile' named entity 'serotype' named entity 'control participants' named entity 'intravenous immunoglobulin' named entity 'etiology' named entity 'serotype' named entity 'young children' named entity 'rash' named entity 'incidence rates' named entity 'intravenous immunoglobulin' named entity 'PCR' named entity 'human embryonic'

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