About: Comparison of Mental Health Symptoms Prior to and During COVID-19 among Patients with Systemic Sclerosis from Four Countries: A Scleroderma Patient-centered Intervention Network (SPIN) Cohort Study

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About: Comparison of Mental Health Symptoms Prior to and During COVID-19 among Patients with Systemic Sclerosis from Four Countries: A Scleroderma Patient-centered Intervention Network (SPIN) Cohort Study Goto Sponge NotDistinct Permalink

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Comparison of Mental Health Symptoms Prior to and During COVID-19 among Patients with Systemic Sclerosis from Four Countries: A Scleroderma Patient-centered Intervention Network (SPIN) Cohort Study
Creator	Mouthon, Luc City, Mexico De, Servicio Lewis, Nancy Paul's Hospital, St Scotia, Nova Zubirán, Nutrición Ontario, Canada Benedetti, Andrea Patten, Scott Rice, Danielle Thombs, Brett Bartlett, Susan Médicas, Ciencias Paul', St Nacional, Instituto Assistance, Atlantic, Scleroderma Bernstein, Elana Bourgeault, Angelica Bustamante, Laura Carboni-Jiménez, Andrea Carrier, Marie-Eve Centre, Hospitalier Chaigne, Benjamin Duchek, Delaney Dunne, James Fortin, Paul Gagarine, Maria Harb, Sami Henry, Richard Herrick, Ariane Jones, Niall Kafaja, Suzanne Kwakkenbos, Linda Malcarne, Vanessa Manning, Joanne Mayes, Maureen Nordlund, Julia Proudman, Susanna Rannou, François Reyna, Rodriguez Richard, Michelle Robinson, Rodriguez, Esther Régional, Sauvé, Maureen Schouffoer, Anne Sobanski, Vincent Sofia, Tatiana Suarez-Almazor, Maria Tao, Lydia Thorne, Carter Turner, Kimberly Varga, John Wilcox, Pearce
Source	MedRxiv
abstract	Background: No studies have reported comparisons of mental health symptoms prior to and during COVID-19 in vulnerable populations. Objectives were to compare anxiety and depression symptoms among people with a pre-existing medical condition, the autoimmune disease systemic sclerosis (SSc; scleroderma), including continuous change scores, proportion with change [≥] 1 minimal clinically important difference (MCID), and factors associated with changes, including country. Methods: Pre-COVID-19 Scleroderma Patient-centered Intervention Network Cohort data were linked to COVID-19 data collected April 9 to April 27, 2020. Anxiety symptoms were assessed with the PROMIS Anxiety 4a v1.0 scale (MCID = 4 points) and depression symptoms with the Patient Health Questionnaire-8 (MCID = 3 points). Multiple linear and logistic regression were used to assess factors associated with continuous change and change [≥] 1 MCID. Findings: Among 435 participants (Canada = 98; France = 159; United Kingdom = 50; United States = 128), mean anxiety symptoms increased 4.9 points (95% confidence interval [CI] 4.0 to 5.7). Depression symptom change was negligible (0.3 points; 95% CI -0.7 to 0.2). Compared to France, adjusted scores from the United States and United Kingdom were 3.8 points (95% CI 1.7 to 5.9) and 2.9 points higher (95% CI 0.0 to 5.7); scores for Canada were not significantly different. Odds of increasing by [≥] 1 MCID were twice as high for the United Kingdom (2.0, 95% CI 1.0 to 4.2) and United States (1.9, 95% CI 1.1 to 3.2). Participants who used mental health services pre-COVID had adjusted increases 3.7 points (95% CI 1.7 to 5.7) less than other participants. Interpretation: Anxiety symptoms, but not depression symptoms, increased dramatically during COVID-19 among people with a pre-existing medical condition. Increase was larger in the United Kingdom and United States than in Canada and France but substantially less for people with pre-COVID-19 mental health treatment.
has issue date	2020-06-16(xsd:dateTime)
bibo:doi	10.1101/2020.06.13.20128694
has license	medrxiv
sha1sum (hex)	7a0c7f68f145ab96106e4b9869cdd94e0ec92eff
schema:url	https://doi.org/10.1101/2020.06.13.20128694
resource representing a document's title	Comparison of Mental Health Symptoms Prior to and During COVID-19 among Patients with Systemic Sclerosis from Four Countries: A Scleroderma Patient-centered Intervention Network (SPIN) Cohort Study
resource representing a document's body	covid:7a0c7f68f145ab96106e4b9869cdd94e0ec92eff#body_text
is schema:about of	named entity 'factors' named entity 'Cohort' named entity 'Prior' named entity 'Symptoms' named entity 'systemic sclerosis' named entity 'COVID-19' named entity 'populations' named entity 'Objectives' named entity 'depression' named entity 'autoimmune disease' named entity 'systemic sclerosis' named entity 'scleroderma' named entity 'MCID' named entity 'minimal clinically important difference' named entity 'Cohort Study' named entity 'symptoms' named entity 'COVID-19' named entity 'medRxiv' named entity 'general mental health' named entity 'preprint' named entity 'doi' named entity 'anxiety' named entity 'preprint' named entity 'effect size' named entity 'symptom' named entity 'France' named entity 'mental health' named entity 'individual participant data' named entity 'study protocol' named entity 'France'

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