About: Lung innervation in the eye of a cytokine storm: neuroimmune interactions and COVID-19

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Lung innervation in the eye of a cytokine storm: neuroimmune interactions and COVID-19 Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Lung innervation in the eye of a cytokine storm: neuroimmune interactions and COVID-19
Creator	De Virgiliis, Francesco Giovanni, Simone
Source	Medline; PMC
abstract	COVID-19 is an infectious disease caused by the coronavirus SARS-CoV-2, which was first reported in Wuhan, China, in December 2019 and has caused a global pandemic. Acute respiratory distress syndrome (ARDS) is a common feature of severe forms of COVID-19 and can lead to respiratory failure, especially in older individuals. The increasing recognition of the neurotropic potential of SARS-CoV-2 has sparked interest in the role of the nervous system in respiratory failure in people with COVID-19. However, the neuroimmune interactions in the lung in the context of ARDS are poorly understood. In this Perspectives article, we propose the concept of the neuroimmune unit as a critical determinant of lung function in the context of COVID-19, inflammatory conditions and ageing, focusing particularly on the involvement of the vagus nerve. We discuss approaches such as neurostimulation and pharmacological neuromodulation to reduce tissue inflammation with the aim of preventing respiratory failure.
has issue date	2020-08-25(xsd:dateTime)
bibo:doi	10.1038/s41582-020-0402-y
bibo:pmid	32843733
has license	no-cc
sha1sum (hex)	79d168a2dbf95780988feea63c2b2fd90b1bb14c
schema:url	https://doi.org/10.1038/s41582-020-0402-y
resource representing a document's title	Lung innervation in the eye of a cytokine storm: neuroimmune interactions and COVID-19
has PubMed Central identifier	PMC7446605
has PubMed identifier	32843733
schema:publication	Nat Rev Neurol
resource representing a document's body	covid:79d168a2dbf95780988feea63c2b2fd90b1bb14c#body_text
is schema:about of	named entity 'SARS-CoV-2' named entity 'inflammatory' named entity 'neuroimmune' named entity 'ARDS' named entity 'DISCUSS' named entity 'CONTEXT' named entity 'DECEMBER' named entity 'AGEING' named entity 'LUNG' named entity 'severe' named entity 'unit' named entity 'potential' named entity 'caused' named entity 'ARDS' named entity 'Wuhan' named entity 'interactions' named entity 'concept' named entity 'COVID' named entity 'SARS-CoV-2' named entity 'respiratory failure' named entity 'Wuhan' named entity 'ARDS' named entity 'pharmacological' named entity 'China' named entity 'COVID-19' named entity 'physiology' named entity 'IFNγ' named entity 'enteric neurons' named entity 'infectivity' named entity 'vasodilation' named entity 'heterogeneity' named entity 'infection' named entity 'viral infection' named entity 'COVID' named entity 'mAChR' named entity 'inflammatory response' named entity 'lipopolysaccharide' named entity 'NK cells' named entity 'M2 receptor' named entity 'mucociliary clearance' named entity 'vagal' named entity 'cation' named entity 'lungs' named entity 'neurons' named entity 'IL-1β' named entity 'COVID-19' named entity 'parainfluenza virus' named entity 'CX3CR1' named entity 'vagus nerve' named entity 'SARS-CoV-2' named entity 'infection' named entity 'macrophage' named entity 'Alveolar epithelial cells' named entity 'trachea' named entity 'macrophages' named entity 'Immune responses' named entity 'anatomy' named entity 'lung physiology' named entity 'immune response' named entity 'serine' named entity 'alveolar' named entity 'macrophages' named entity 'SARS-CoV' named entity 'immune cell' named entity 'cell types' named entity 'vagal' named entity 'immunocompromised' named entity 'immune cells' named entity 'Middle East respiratory syndrome coronavirus' named entity 'NL63' named entity 'phagocytosis' named entity 'vagus nerve' named entity 'respiratory tract' named entity 'tumour necrosis factor' named entity 'infection' named entity 'lungs' named entity 'lung inflammation' named entity 'CGRP' named entity 'acetylcholine' named entity 'CGRP'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software