About: Interactions of particulate matter and pulmonary surfactant: implications for human health

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Interactions of particulate matter and pulmonary surfactant: implications for human health
Creator	Liu, Jifang Wang, Feifei Zeng, Hongbo
Source	Elsevier; PMC
abstract	Particulate matter (PM), which is the primary contributor to air pollution, has become a pervasive global health threat. When PM enters into a respiratory tract, the first body tissues to be directly exposed are the cells of respiratory tissues and pulmonary surfactant. Pulmonary surfactant is a pivotal component to modulate surface tension of alveoli during respiration. A lot of studies have proved that PM would interact with pulmonary surfactant to affect the alveolar activity, and meanwhile, pulmonary surfactant would be adsorbed to the surface of PM to change the toxic effect of PM. This review focuses on recent studies of the interactions between micro/nanoparticles (synthesized and environmental particles) and pulmonary surfactant (natural surfactant and its models), as well as the health effects that caused by PM through a few significant aspects, such as surface properties of PM, including size, surface charge, hydrophobicity, shape, chemical nature, etc. Moreover, in vitro and in vivo studies showed that PM leads to oxidative stress, inflammatory response, fibrosis, and cancerization in living bodies. By providing a comprehensive picture of PM-surfactant interaction, this review will benefit both researchers for further studies and policy-makers for setting up more appropriate regulations to reduce the adverse effects of PM on public health.
has issue date	2020-08-19(xsd:dateTime)
bibo:doi	10.1016/j.cis.2020.102244
has license	no-cc
sha1sum (hex)	7895cdf10cd01d52e7baca1e42747d4ae6b99b56
schema:url	https://doi.org/10.1016/j.cis.2020.102244
resource representing a document's title	Interactions of particulate matter and pulmonary surfactant: implications for human health
has PubMed Central identifier	PMC7435289
schema:publication	Adv Colloid Interface Sci
resource representing a document's body	covid:7895cdf10cd01d52e7baca1e42747d4ae6b99b56#body_text
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