About: Characteristics of laboratory findings of COVID-19 patients with comorbid diabetes mellitus

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Characteristics of laboratory findings of COVID-19 patients with comorbid diabetes mellitus
Creator	Wang, Xiao Chen, Yong Liu, Jun Li, Na Wang, X Liang, Jing Chen, Y Liu, J Shao, J Tang, Min Liang, J Li, N Li, ，na Shao, Jiaqing Tang, M Ye, Bo Ye, B
source	Elsevier; Medline; PMC
abstract	AIMS: Coronavirus disease (COVID-19), also referred to as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is instigated by a novel coronavirus. The disease was initially reported in Wuhan, China, in December 2019. Diabetes is a risk factor associated with adverse outcomes. Herein, our objective was to investigate the characteristics of laboratory findings of type 2 diabetes mellitus (T2DM) patients infected with SARS-CoV-2. METHODS: This was a retrospective study and included 80 T2DM patients of Jinling Hospital from 2010–2020, as well as 76 COVID-19 patients without T2DM and 55 COVID-19 patients with T2DM who were treated at Huoshen hill Hospital from February 11 to March 18, 2020. We then compared the differences in laboratory test results between the three groups. RESULTS: The levels of lymphocytes, uric acid (UA), and globulin in the T2DM group were significantly higher. In contrast, C-reactive protein (CRP), creatinine, and lactic dehydrogenase (LDH)levels were lower than those in the COVID-19 (p ＜ 0.05) and COVID-19 + T2DM groups (p ＜ 0.05). No considerable difference was observed regarding the levels of alanine aminotransferase (ALT), white blood cell (WBC), aspartate aminotransferase (AST), globulin, and blood urea nitrogen (BUN) in the three groups (p＞0.05). CONCLUSION: T2DM patients infected with SARS-CoV-2 showed decreased levels of body mass index (BMI), lymphocytes, UA, and albumin, and increased CRP levels. The decreased BMI, UA, and albumin levels may be associated with oxidative stress response and nutritional consumption. The decreased lymphocyte counts and increased CRP levels may be related to the infection.
has issue date	2020-07-22(xsd:dateTime)
bibo:doi	10.1016/j.diabres.2020.108351
bibo:pmid	32711001
has license	no-cc
sha1sum (hex)	77297012bfd2c7cb4d03770181e12aa1c1c27cd4
schema:url	https://doi.org/10.1016/j.diabres.2020.108351
resource representing a document's title	Characteristics of laboratory findings of COVID-19 patients with comorbid diabetes mellitus
has PubMed Central identifier	PMC7375292
has PubMed identifier	32711001
schema:publication	Diabetes Res Clin Pract
resource representing a document's body	covid:77297012bfd2c7cb4d03770181e12aa1c1c27cd4#body_text
is schema:about of	named entity 'patients' named entity 'disease' named entity 'infected' named entity 'CHARACTERISTICS' named entity 'REFERRED TO' named entity 'DISEASE' named entity 'Coronavirus' named entity 'referred' named entity 'COVID-19' named entity 'Characteristics' named entity 'Coronavirus disease' named entity 'CRP' named entity 'signs and symptoms' named entity 'Diabetes' named entity 'China' named entity 'metabolic' named entity 'T2DM' named entity 'DBP' named entity 'Albumin' named entity 'COVID-19' named entity 'T2DM' named entity 'food consumption' named entity 'chi-square test' named entity 'T2DM' named entity 'T2DM' named entity 'COVID-19' named entity 'ROS' named entity 'comorbidities' named entity 'free radicals' named entity 'lymphocytes' named entity 'T2DM' named entity 'BMI' named entity 'T2DM' named entity 'T2DM' named entity 'oxidative stress' named entity 'reactive oxygen species' named entity 'antioxidant' named entity 'malnutrition' named entity 'superoxide' named entity 'SBP' named entity 'Laboratory tests' named entity 'antioxidants' named entity 'enzyme' named entity 'BMI' named entity 'Diastolic blood pressure' named entity 'plasma' named entity 'albumin' named entity 'BMI' named entity 'national health commission' named entity 'antioxidant' named entity 'SPSS' named entity 'COVID' named entity 'inflammation' named entity 'nutritional status' named entity 'COVID' named entity 'ROS' named entity 'mmol/L' named entity 'pulmonary disease' named entity 'physiological' named entity 'T2DM' named entity 'creatinine levels' named entity 'COVID' named entity 'BMI' named entity 'BMI' named entity 'confounding'

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