About: Effect of integrated traditional Chinese medicine and western medicine on the treatment of severe acute respiratory syndrome: A meta-analysis

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About: Effect of integrated traditional Chinese medicine and western medicine on the treatment of severe acute respiratory syndrome: A meta-analysis Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Effect of integrated traditional Chinese medicine and western medicine on the treatment of severe acute respiratory syndrome: A meta-analysis
Creator	Chen, Yan Guo, Jeff Healy, Daniel Mph, Chen, Siyan Dp, Healy Jj, Guo Pharmacoeconoomics, Pharmd, Daniel Siyan, Zhan
source	Medline; PMC
abstract	BACKGROUND: Data regarding the treatment efficacy of integrative treatment of Traditional Chinese Medicine (TCM) and Western Medicine (WM) in treating patients with (SARS) are conflicting. The effects of integrative TCM/WM treatment have not been fully quantified. OBJECTIVES: To systematically asses the treatment effects of integrated TCM with WM versus WM alone in patients with SARS, incorporating data from recently published studies. METHODS: A meta-analysis was conducted, using published randomized and nonrandomized controlled clinical studies that compared the treatment effects of integrative TCM/WM with WM alone from 2002 to 2006. The outcome measurements included mortality rate, cure rate, resolution of pulmonary infiltrate, use of corticosteroid, and time to defervescence. The effect sizes were presented as risk ratio (RR), rate difference (RD), and weighted mean difference (WMD). The pooled effect sizes were calculated by both fixed-effects and random-effects models. RESULTS: A total of 1,678 patients with a diagnosis of SARS were identified, including 866 patients from 16 randomized controlled studies and 812 patients from 8 nonrandomized controlled studies. There were no differences detected in mortality rate or cure rate between treatments. Compared with patients receiving WM treatment alone, patients receiving integrative treatment were more likely to have complete or partial resolution of pulmonary infiltrate (RD=0.18, 95%CI; 0.07 to 0.30), lower average daily dosage (mg) of corticosteroid (WMD=-60.27, 95% CI; -70.58 to -49.96), higher CD4+ counts (cells/uL) (WMD=167.96, 95% CI; 109.68 to 226.24), and shorter time to defervescence (days) (WMD= -1.06, 95%CI;-1.60 to -0.53). CONCLUSIONS: The experience of integrative TCM/WM in the treatment of SARS is encouraging. The use of TCM as an adjunctive therapy in the treatment of SARS should be further investigated.
has issue date	2007-04-02(xsd:dateTime)
bibo:pmid	25214911
has license	cc-by-nc-sa
sha1sum (hex)	756dbc931627ce595e70224e084e8cb89d38287c
resource representing a document's title	Effect of integrated traditional Chinese medicine and western medicine on the treatment of severe acute respiratory syndrome: A meta-analysis
has PubMed Central identifier	PMC4155143
has PubMed identifier	25214911
schema:publication	Pharm Pract (Granada)
resource representing a document's body	covid:756dbc931627ce595e70224e084e8cb89d38287c#body_text
is schema:about of	named entity 'WESTERN MEDICINE' named entity 'PHARMACY PRACTICE' named entity 'TRADITIONAL CHINESE MEDICINE' named entity 'INTEGRATED' named entity 'META-ANALYSIS' named entity 'TREATMENT' named entity 'EFFECT' named entity 'SEVERE ACUTE RESPIRATORY SYNDROME' named entity 'CHEN' named entity 'GUO' named entity 'HEALY' covid:arg/756dbc931627ce595e70224e084e8cb89d38287c named entity 'meta-analysis' named entity 'meta-analysis' named entity 'western medicine' named entity 'traditional Chinese medicine' named entity 'mortality rate' named entity 'corticosteroids' named entity 'SARS' named entity 'SARS' named entity 'sensitivity analysis' named entity 'fixed-effects' named entity 'mortality rate' named entity 'mortality rate' named entity 'mortality rate' named entity 'SARS' named entity 'randomization' named entity 'mortality rates' named entity 'adverse events' named entity 'sample size' named entity 'cure rate' named entity 'corticosteroids' named entity 'WMD' named entity 'TCM' named entity 'randomization' named entity 'controlled clinical studies' named entity 'corticosteroids' named entity 'cure rate' named entity 'infection' named entity 'lymphopenia' named entity 'significant difference' named entity 'SARS' named entity 'controlled clinical studies' named entity 'WMD' named entity 'SARS' named entity 'adverse events' named entity 'treatment regimens' named entity 'double blinding' named entity 'Cochrane Collaboration' named entity 'femoral head' named entity 'significant difference' named entity 'treatment group' named entity 'cure rate' named entity 'SARS' named entity 'significant difference' named entity 'mortality rate' named entity 'TCM' named entity 'SARS' named entity 'SARS' named entity 'controlled clinical studies' named entity 'corticosteroid' named entity 'cure rate' named entity 'significant difference' named entity 'corticosteroids' named entity 'route of administration' named entity 'corticosteroids' named entity 'treatment group' named entity 'mortality rate' named entity 'RCT' named entity 'SARS' named entity 'SARS' named entity 'randomization' named entity 'TCM' named entity 'adverse events'

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