About: Gene expression profiles alteration after infection of virus, bacteria, and parasite in the Olive flounder (Paralichthys olivaceus)

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About: Gene expression profiles alteration after infection of virus, bacteria, and parasite in the Olive flounder (Paralichthys olivaceus) Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Gene expression profiles alteration after infection of virus, bacteria, and parasite in the Olive flounder (Paralichthys olivaceus)
Creator	Kim, Do-Hyung Ahn, Kung Cha, Hee-Jae Gim, Jeong-An Jo, Ara Kim, Ahran Kim, Heui-Soo Kim, Suhkmann Kim, Woo-Jin Lee, Hee-Eun Mishra, Anshuman Nam, Gyu-Hwi Park, Chan-Il Yoon, Dahye Choi, Yung
Source	PMC
abstract	Olive flounder (Paralichthys olivaceus) is one of economically valuable fish species in the East Asia. In comparison with its economic importance, available genomic information of the olive flounder is very limited. The mass mortality caused by variety of pathogens (virus, bacteria and parasites) is main problem in aquaculture industry, including in olive flounder culture. In this study, we carried out transcriptome analysis using the olive flounder gill tissues after infection of three types of pathogens (Virus; Viral hemorrhagic septicemia virus, Bacteria; Streptococcus parauberis, and Parasite; Miamiensis avidus), respectively. As a result, we identified total 12,415 differentially expressed genes (DEG) from viral infection, 1,754 from bacterial infection, and 795 from parasite infection, respectively. To investigate the effects of pathogenic infection on immune response, we analyzed Gene ontology (GO) enrichment analysis with DEGs and sorted immune-related GO terms per three pathogen groups. Especially, we verified various GO terms, and genes in these terms showed down-regulated expression pattern. In addition, we identified 67 common genes (10 up-regulated and 57 down-regulated) present in three pathogen infection groups. Our goals are to provide plenty of genomic knowledge about olive flounder transcripts for further research and report genes, which were changed in their expression after specific pathogen infection.
has issue date	2018-12-24(xsd:dateTime)
bibo:doi	10.1038/s41598-018-36342-y
bibo:pmid	30584247
has license	cc-by
sha1sum (hex)	70fe1da70b714ba14f71d217ecf93da18e291aa7
schema:url	https://doi.org/10.1038/s41598-018-36342-y
resource representing a document's title	Gene expression profiles alteration after infection of virus, bacteria, and parasite in the Olive flounder (Paralichthys olivaceus)
has PubMed Central identifier	PMC6305387
has PubMed identifier	30584247
schema:publication	Sci Rep
resource representing a document's body	covid:70fe1da70b714ba14f71d217ecf93da18e291aa7#body_text
is schema:about of	named entity 'INFECTION' named entity 'GENE EXPRESSION PROFILES' named entity 'specific' named entity 'infection' named entity 'expressed genes' named entity 'Streptococcus' named entity 'down-regulated' named entity 'PARASITE' named entity 'CAUSED BY' named entity '795' named entity 'BACTERIAL INFECTION' named entity 'MIAMIENSIS AVIDUS' named entity 'ENRICHMENT ANALYSIS' named entity 'GROUPS' named entity 'ITS' named entity 'ADDITION' named entity 'OUR' named entity 'USING' named entity 'TRANSCRIPTS' named entity 'EXPRESSED' named entity 'CULTURE' named entity 'UP-REGULATED' named entity 'CHANGED' named entity 'GENES' named entity 'TISSUES' named entity 'ABOUT' named entity 'RESULT' named entity 'DOWN-REGULATED EXPRESSION' named entity 'TERMS' named entity 'MASS MORTALITY' named entity 'IMMUNE' named entity 'BACTERIA' named entity 'GENOMIC' named entity 'TYPES' named entity 'VERY LIMITED' named entity 'RELATED' named entity 'KNOWLEDGE' named entity 'PRESENT' named entity 'EFFECTS' named entity 'TRANSCRIPTOME ANALYSIS' named entity 'DEGS' named entity 'PLENTY' named entity 'PARASITES' named entity 'TOTAL' named entity 'CARRIED' named entity 'GENE ONTOLOGY' named entity 'OLIVE FLOUNDER' named entity 'VERIFIED' named entity 'BACTERIA ' named entity 'STUDY' named entity 'SORTED' named entity 'AQUACULTURE' named entity 'RESEARCH' named entity 'THESE' named entity 'VIRAL HEMORRHAGIC SEPTICEMIA VIRUS' named entity 'GENOMIC INFORMATION' named entity 'OPEN' named entity 'COMPARISON' named entity 'ANALYZED' named entity 'EXPRESSION' named entity 'VARIETY' named entity 'SPECIFIC' named entity 'MAIN' named entity 'AVAILABLE' named entity 'GILL' named entity 'VIRUS' named entity 'BACTERIA'

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