About: Clinical, laboratory, and radiological features indicative of novel coronavirus disease (COVID‐19) in emergency departments – a multicentre case‐control study in Hong Kong

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About: Clinical, laboratory, and radiological features indicative of novel coronavirus disease (COVID‐19) in emergency departments – a multicentre case‐control study in Hong Kong Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Clinical, laboratory, and radiological features indicative of novel coronavirus disease (COVID‐19) in emergency departments – a multicentre case‐control study in Hong Kong
Creator	Chan, Lau, Yin Leung, Wong, Graham, A Woo, Yat Lam, Kin Pui, Rex Hung, Ching Kei, Kevin Lui, Chin, San Chiu, Prof Chun, Tat Colin, Prof Ho, Eric Ion, Wa Kin, Ling Kin, Wa
Source	Medline; PMC
abstract	OBJECTIVES: Little is known about the value of routine clinical assessment in identifying patients with coronavirus disease 2019 (COVID‐19) in the emergency department (ED). We aimed to compare the exposure history, signs and symptoms, laboratory, and radiographic features of ED patients who tested positive and negative for COVID‐19. METHODS: This was a case‐control study in seven EDs in Hong Kong from 20 January to 29 February 2020. Thirty‐seven patients with laboratory‐confirmed COVID‐19 were age‐ and gender‐matched to 111 controls. We compared the groups with univariate analysis and calculated the odds ratio (OR) of having COVID‐19 for each characteristic that was significantly different between the groups with adjustment for age and presumed location of acquiring the infection. RESULTS: There were no significant differences in patient characteristics and reported symptoms between the groups. A positive contact history within 14 days (adjusted OR 37.61, 95% CI 10.86‐130.19), bilateral chest radiograph shadow (adjusted OR 13.19, 95% CI 4.66‐37.35), having prior medical consultation (adjusted OR 7.43, 95% 2.89 ‐19.09), a lower white blood cell count (adjusted OR 1.30, 95% CI 1.11‐1.51), and a lower platelet count (adjusted OR 1.07, 95% CI 1.01‐1.12) were associated with a higher odds of COVID‐19 separately. A higher neutrophil count was associated with a lower odds of COVID‐19 (adjusted OR 0.77, 95% CI 0.65‐0.91). CONCLUSION: This study highlights a number of clinical features that may be useful in identifying high‐risk patients for early testing and isolation while waiting for the test result. Further studies are warranted to verify the findings. This article is protected by copyright. All rights reserved
has issue date	2020-06-20(xsd:dateTime)
bibo:doi	10.1002/emp2.12183
bibo:pmid	32838379
has license	no-cc
sha1sum (hex)	6fd579d8a403627887c8fa5b422dfeacd80ccc4b
schema:url	https://doi.org/10.1002/emp2.12183
resource representing a document's title	Clinical, laboratory, and radiological features indicative of novel coronavirus disease (COVID‐19) in emergency departments – a multicentre case‐control study in Hong Kong
has PubMed Central identifier	PMC7323237
has PubMed identifier	32838379
schema:publication	J Am Coll Emerg Physicians Open
resource representing a document's body	covid:6fd579d8a403627887c8fa5b422dfeacd80ccc4b#body_text
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