About: Adult bacterial nasopharyngitis: A clinical entity?

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Adult bacterial nasopharyngitis: A clinical entity?
Creator	Heald, Alison Auckenthaler, Raymond Borst, Olga Delaspre, Daniel Germann, Lukas Kaiser, Hans Matter, Laurent Stalder,
Source	PMC
abstract	Objective: To investigate bacterial nasopharyngitis as a cause of adult upper respiratory infection. Design: Prospective case series. Setting: Walk-in medical clinic of a university hospital. Patients: 507 patients with cold or flu symptoms, sore throat, or recent cough; 21 control subjects without symptoms of upper respiratory infection. Measurements and main results: After thorough history and physical examination, the patients underwent nasopharyngeal aspiration and throat culture. Nasopharyngeal specimens were cultured for both bacteria and viruses; antigens for influenza, parainfluenza, and respiratory syncytial virus were sought by enzyme-linked immunosorbent assay (ELISA); serum antibodies to viral respiratory pathogens were determined. Group A beta-hemolytic streptococci grew from the throat specimens of 39 of the 507 patients (8%) or 38 of 3 34 patients (11%) who had clinical diagnoses of pharyngitis. Thirty-three cases of influenza A, 20 cases of influenza B, and seven cases of parainfluenza infections were diagnosed. Bacteria were cultured from the nasopharyngeal secretions of 284 patients (56%). In contrast to pharyngeal culture, commensal mixed flora were rarely found in nasopharyngeal culture. Nasopharyngeal culture of bacteria usually considered to be respiratory pathogens was significantly associated with the presence of leukocytes.Streptococcus pneumoniae (odds ratio 6.0, 95% confidence interval 2.6–14.2),Moraxella catarrbalis (odds ratio 12.9, 95% confidence interval 3.1–79.5), andHemophilus influenzae (odds ratio 3.0, 95% confidence interval 1.2–7.4) were all associated with the presence of leukocytes. In contrast, nasophaiyngeal culture of coagulase-negative staphylococci, mixed flora, and the documentation of a viral infection were not associated with the presence of leukocytes. For none of 21 control subjects were “pathogenic” bacteria found. Conclusions: These data suggest that potentially pathogenic bacteria may have a causal role in adult nasopharyngitis, although further data are needed to confirm this hypothesis.
has issue date	1993-12-01(xsd:dateTime)
bibo:doi	10.1007/bf02598283
bibo:pmid	8120682
has license	no-cc
sha1sum (hex)	6e1c41f42300b4c328b7686b4fe370aa55681bcc
schema:url	https://doi.org/10.1007/bf02598283
resource representing a document's title	Adult bacterial nasopharyngitis: A clinical entity?
has PubMed Central identifier	PMC7089105
has PubMed identifier	8120682
schema:publication	J Gen Intern Med
resource representing a document's body	covid:6e1c41f42300b4c328b7686b4fe370aa55681bcc#body_text
is schema:about of	covid:arg/6e1c41f42300b4c328b7686b4fe370aa55681bcc named entity 'bacterial' named entity 'nasopharynx' named entity 'rhinitis' named entity 'antibiotics' named entity 'parainfluenza' named entity 'bacteria' named entity 'Streptococcus pneumoniae' named entity 'cough' named entity 'viral infection' named entity 'fever' named entity 'nasopharyngeal' named entity 'S. pneumoniae' named entity 'Savyon' named entity 'inflammation' named entity 'Switzerland' named entity 'upper respiratory infections' named entity 'nasopharynx' named entity 'group A streptococci' named entity 'follow-up' named entity 'organism' named entity 'viral infections' named entity 'nasopharyngitis' named entity 'viral infection' named entity 'housestaff' named entity 'investigate' named entity 'S. pneumoniae' named entity 'leukocytes' named entity 'viral infection' named entity 'etiology' named entity 'nasopharynx' named entity 'otitis media' named entity 'smokers' named entity 'Microimmunofluorescence' named entity 'bacteria' named entity 'IgG' named entity 'sore throat' named entity 'sinusitis' named entity 'sloughing' named entity 'leukocytes' named entity 'IgM antibodies' named entity 'nasopharynx' named entity 'sheep' named entity 'Corynebacteria' named entity 'leukocytes' named entity 'informed consent' named entity 'nasopharyngeal secretions' named entity 'H. influenzae' named entity 'nasopharynx' named entity 'purulent' named entity 'serum' named entity 'pneumonia' named entity 'group A streptococci' named entity 'pharynx' named entity 'group A streptococci' named entity 'viruses' named entity 'upper respiratory infection' named entity 'upper respiratory infection' named entity 'upper respiratory infection' named entity 'influenza' named entity 'influenza' named entity 'clinical diagnoses' named entity 'antibodies' named entity 'cytomegalovirus' named entity 'pneumococci' named entity 'nalidixic acid' named entity 'aspirate' named entity 'Mycoplasma' named entity 'sinuses' named entity 'Medac' named entity 'antibiotics' named entity 'nasopharynx' named entity 'leukocytes' named entity 'respiratory tract infection'

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