About: Kidney Transplantation in the Times of COVID-19

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About: Kidney Transplantation in the Times of COVID-19 – A Literature Review Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Kidney Transplantation in the Times of COVID-19 – A Literature Review
Creator	Imam, Ashraf Merhav, Hadar Abcef, Abed Abukhalaf, A Acd, Abu-Gazala Ashraf, Acdef Khalaileh, Riham, Bcd Sadi, Abcef Samir, Aef
Source	PMC
abstract	Kidney transplantation at the time of the COVID-19 pandemic is challenging. Modifying the immunosuppression protocols is controversial and not evidence based. In this study, we aim to review the published literature of kidney transplant recipients who encountered COVID-19. A literature review was performed using PubMed, ScienceDirect, and World Health Organization databases to identify relevant English-language articles published up to May 7, 2020. There were 24 articles that reported 129 kidney transplant recipients who encountered COVID-19. The age mean was 54.2 years with 73.7% as males. The most commonly reported presentations in order were fever (82.3%), cough (58%), shortness of breath (33.2%), and fatigue (30.7%). Acute kidney injury was observed in 34.1% of patients. Kidney transplant patients encountered COVID-19 were maintained on tacrolimus (Tac, 92%), mycophenolate mofetil (MMF, 78.8%), and prednisone (Pred, 77%) and were manage by holding MMF in 79.1% of patients and holding Tac in 34.4% of patients. In all, 20% of patients needed Intensive Care Unit (ICU) admission and 24.6% of patients required mechanical ventilation. In all, 18.8% of patients had died compared to the reported general population COVID-19 mortality of 3.4%. The clinical presentation of COVID-19 in kidney transplant recipients may be different from the general population with a higher rate of severe disease, complications including renal failure, and mortality.
has issue date	2020-07-24(xsd:dateTime)
bibo:doi	10.12659/aot.925755
bibo:pmid	32703929
has license	cc-by-nc-nd
sha1sum (hex)	6da1b4c2e94c64698e9709fe758d2b7f91ce9f38
schema:url	https://doi.org/10.12659/aot.925755
resource representing a document's title	Kidney Transplantation in the Times of COVID-19 – A Literature Review
has PubMed Central identifier	PMC7409595
has PubMed identifier	32703929
schema:publication	Ann Transplant
resource representing a document's body	covid:6da1b4c2e94c64698e9709fe758d2b7f91ce9f38#body_text
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