About: Long-term viremia and fecal shedding in pups after modified-live canine parvovirus vaccination

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About: Long-term viremia and fecal shedding in pups after modified-live canine parvovirus vaccination Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Long-term viremia and fecal shedding in pups after modified-live canine parvovirus vaccination
Creator	Buonavoglia, Canio Decaro, Nicola Desario, Costantina Cavalli, Alessandra Losurdo, Michele Ventrella, Gianpiero Aulicino, Stefano Crescenzo, Giuseppe Rizzi, Stefania Colaianni, Maria Lucente, Maria
Source	Elsevier; Medline; PMC
abstract	Abstract Canine parvovirus (CPV) modified live virus vaccines are able to infect vaccinated dogs replicating in the bloodstream and enteric mucosa. However, the exact duration and extent of CPV vaccine-induced viremia and fecal shedding are not known. With the aim to fill this gap, 26 dogs were administered two commercial vaccines containing a CPV-2 or CPV-2b strain and monitored for 28 days after vaccination. By using real-time PCR, vaccine-induced viremia and shedding were found to be long lasting for both vaccinal strains. Vaccinal CPV-2b shedding was detected for a shorter period than CPV-2 (12 against 19 mean days) but with greater viral loads, whereas viremia occurred for a longer period (22 against 19 mean days) and with higher titers for CPV-2b. Seroconversion appeared as early as 7 and 14 days post-vaccination for CPV-2b and CPV-2 vaccines, respectively. With no vaccine there was any diagnostic interference using in-clinic or hemagglutination test, since positive results were obtained only by fecal real-time PCR testing. The present study adds new insights into the CPV vaccine persistence in the organism and possible interference with diagnostic tests.
has issue date	2014-06-24(xsd:dateTime)
bibo:doi	10.1016/j.vaccine.2014.04.050
bibo:pmid	24793948
has license	els-covid
sha1sum (hex)	6bd909db67202372c9d945f9678b91aedd952ca1
schema:url	https://doi.org/10.1016/j.vaccine.2014.04.050
resource representing a document's title	Long-term viremia and fecal shedding in pups after modified-live canine parvovirus vaccination
has PubMed Central identifier	PMC7115601
has PubMed identifier	24793948
schema:publication	Vaccine
resource representing a document's body	covid:6bd909db67202372c9d945f9678b91aedd952ca1#body_text
is schema:about of	named entity 'VACCINATION' named entity 'LIVE' named entity 'long' named entity 'However' named entity 'enteric' named entity 'Long-term' named entity 'LONG-TERM' named entity 'CANINE PARVOVIRUS' named entity 'POST' named entity 'FECAL' named entity 'PUPS' named entity 'LIVE' named entity 'VACCINE' named entity 'INSIGHTS' named entity 'DURATION' named entity 'NEW' named entity 'EXACT' named entity 'REAL-TIME PCR' named entity 'PRESENT' named entity 'HIGHER' named entity 'VACCINES' named entity 'FOUND' named entity 'ADMINISTERED' named entity 'OCCURRED' named entity 'DETECTED' named entity 'TESTING' named entity 'MEAN' named entity 'EXTENT OF' named entity 'USING' named entity 'POSITIVE' named entity 'RESULTS' named entity 'COMMERCIAL' named entity 'SEROCONVERSION' named entity 'PERSISTENCE' named entity 'MODIFIED' named entity 'TO INFECT' named entity 'VIREMIA' named entity 'SHEDDING' named entity 'INTERFERENCE' named entity 'ENTERIC' named entity 'EARLY' named entity 'STRAIN' named entity 'DIAGNOSTIC' named entity 'PERIOD' named entity 'VIRAL' named entity 'FECAL' named entity 'CPV' named entity 'MODIFIED' named entity 'CONTAINING' named entity 'HEMAGGLUTINATION TEST' named entity 'NOT KNOWN' named entity 'STRAINS' named entity 'GAP' named entity 'BUT' named entity 'INDUCED' named entity 'VACCINATION' named entity 'STUDY' named entity 'POSSIBLE' named entity 'OBTAINED' named entity 'VIRUS' named entity 'AIM' named entity 'BLOODSTREAM' named entity 'MONITORED' named entity 'DIAGNOSTIC TESTS' named entity 'ORGANISM' named entity 'CANINE PARVOVIRUS' named entity 'GREATER' named entity 'DOGS' named entity 'REAL-TIME PCR ' named entity 'MUCOSA' named entity 'REPLICATING'

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