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About:
Comparison of different samples for 2019 novel coronavirus detection by nucleic acid amplification tests
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An Entity of Type :
schema:ScholarlyArticle
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covidontheweb.inria.fr
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Type:
Academic Article
research paper
schema:ScholarlyArticle
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type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
has title
Comparison of different samples for 2019 novel coronavirus detection by nucleic acid amplification tests
Creator
Shi, Yi
Jiang, Li
Shi, Yang
Yu, Hua
Pu, Hong
Chen, Xuemei
Gong, Bo
Huang, Guo
Jiang, Lingxi
Lin, He
Long, Bo
Ma, Shi
Si, Guo
Xie, Chunbao
Yang, Xingxiang
Yang, Zhenglin
Source
Elsevier; Medline; PMC
abstract
An ongoing outbreak of severe respiratory pneumonia associated with the 2019 novel coronavirus has recently emerged in China. Here we report the epidemiological, clinical, laboratory and radiological characteristics of 19 suspect cases. We compared the positive ratio of 2019-nCoV nucleic acid amplification test results from different samples including oropharyngeal swab, blood, urine and stool with 3 different fluorescent RT-PCR kits. Nine out of the 19 patients had 2019-nCoV infection detected using oropharyngeal swab samples, and the virus nucleic acid was also detected in eight of these nine patients using stool samples. None of positive results was identified in the blood and urine samples. These three different kits got the same result for each sample and the positive ratio of nucleic acid detection for 2019-nCoV was only 47.4% in the suspect patients. Therefore, it is possible that infected patients have been missed by using nucleic acid detection only. It might be better to make a diagnosis combining the computed tomography scans and nucleic acid detection.
has issue date
2020-02-27
(
xsd:dateTime
)
bibo:doi
10.1016/j.ijid.2020.02.050
bibo:pmid
32114193
has license
no-cc
sha1sum (hex)
6b8344f9f369bdc68e543d3dcca58ecdf57991be
schema:url
https://doi.org/10.1016/j.ijid.2020.02.050
resource representing a document's title
Comparison of different samples for 2019 novel coronavirus detection by nucleic acid amplification tests
has PubMed Central identifier
PMC7129110
has PubMed identifier
32114193
schema:publication
Int J Infect Dis
resource representing a document's body
covid:6b8344f9f369bdc68e543d3dcca58ecdf57991be#body_text
is
schema:about
of
named entity 'NUCLEIC ACID AMPLIFICATION'
named entity 'compared'
named entity 'respiratory'
named entity 'Detection'
named entity 'DIFFERENT'
named entity 'TESTS'
named entity 'COMPARISON'
named entity 'SAMPLES'
named entity 'PNEUMONIA'
named entity 'RESPIRATORY'
named entity 'RECENTLY'
named entity 'CLINICAL'
named entity 'ONGOING'
named entity 'EPIDEMIOLOGICAL'
named entity 'SEVERE'
named entity 'COMPARED'
named entity 'SUSPECT'
named entity 'DETECTION'
named entity '2019 NOVEL CORONAVIRUS'
named entity 'REPORTED'
named entity 'CASES'
named entity 'HERE'
named entity 'LABORATORY'
named entity 'ASSOCIATED WITH'
named entity 'OUTBREAK'
named entity 'CHINA'
named entity 'N A'
named entity '2019 NOVEL CORONAVIRUS'
named entity 'CHARACTERISTICS'
named entity 'ongoing'
named entity 'outbreak'
named entity 'Tests'
named entity 'epidemiological'
named entity 'coronavirus'
named entity '2019 Novel Coronavirus'
named entity 'Nucleic Acid Amplification Tests'
named entity 'median age'
named entity 'ground-glass opacities'
named entity '2019-nCoV'
named entity '2019-nCoV'
named entity 'oropharyngeal'
named entity 'oropharyngeal'
named entity 'nucleic acid test'
named entity 'false negative results'
named entity 'CT scans'
named entity 'NAAT'
named entity 'China'
named entity 'ongoing outbreak'
named entity 'pneumonia'
named entity '2019'
named entity 'China'
named entity 'coronavirus'
named entity 'Here'
named entity '2019'
named entity 'epidemiological'
named entity 'pneumonia'
named entity 'Samples'
named entity 'laboratory'
named entity 'emerged'
named entity 'radiological'
named entity 'severe'
named entity 'suspect'
named entity 'Novel'
named entity '2019'
named entity 'Coronavirus'
named entity 'Nucleic Acid'
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