About: Intragastric immunization with recombinant Lactobacillus casei expressing flagellar antigen confers antibody-independent protective immunity against Salmonella enterica serovar Enteritidis

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About: Intragastric immunization with recombinant Lactobacillus casei expressing flagellar antigen confers antibody-independent protective immunity against Salmonella enterica serovar Enteritidis Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Intragastric immunization with recombinant Lactobacillus casei expressing flagellar antigen confers antibody-independent protective immunity against Salmonella enterica serovar Enteritidis
Creator	Kajikawa, Akinobu Igimi, Shizunobu Satoh, Eiichi Yamamoto, Shigeki Leer, Rob
Source	Elsevier; Medline; PMC
abstract	Abstract A recombinant Lactobacillus casei expressing a flagellar antigen from Salmonella enterica serovar Enteritidis was constructed and evaluated as a mucosal vaccine. Intragastric immunization of the recombinant strain conferred protective immunity against Salmonella infection in mice. This immunization did not result in antigen-specific antibody in either feces or sera but induced the release of IFN-γ on restimulation of primed lymphocytes ex vivo. The results suggested that the protective efficacy provided by flagellin-expressing L. casei is mainly attributable to cell-mediated immune responses. In addition, an adjuvant-type effect of the antigen delivery system with L. casei was also observed.
has issue date	2007-05-04(xsd:dateTime)
bibo:doi	10.1016/j.vaccine.2007.01.055
bibo:pmid	17287050
has license	els-covid
sha1sum (hex)	6a109eb5b0e889ef933943ebf4db5c26cacf85b8
schema:url	https://doi.org/10.1016/j.vaccine.2007.01.055
resource representing a document's title	Intragastric immunization with recombinant Lactobacillus casei expressing flagellar antigen confers antibody-independent protective immunity against Salmonella enterica serovar Enteritidis
has PubMed Central identifier	PMC7115604
has PubMed identifier	17287050
schema:publication	Vaccine
resource representing a document's body	covid:6a109eb5b0e889ef933943ebf4db5c26cacf85b8#body_text
is schema:about of	named entity 'EVALUATED' named entity 'CONSTRUCTED' named entity 'RELEASE' named entity 'CELL' named entity 'PRIMED' named entity 'EX VIVO' named entity 'LACTOBACILLUS CASEI' named entity 'LYMPHOCYTES' named entity 'DELIVERY SYSTEM' named entity 'MUCOSAL VACCINE' named entity 'ANTIGEN DELIVERY' named entity 'IMMUNE RESPONSES' named entity 'INTRAGASTRIC' named entity 'STRAIN' named entity 'IMMUNIZATION' named entity '90%' named entity 'FLAGELLAR' named entity 'IFN' named entity 'TYPE' named entity 'ANTIGEN' named entity 'SPECIFIC ANTIBODY' named entity 'RESULT' named entity 'IMMUNIZATION' named entity 'FLAGELLAR' named entity 'RESULTS' named entity 'FECES' named entity 'SALMONELLA ENTERICA SEROVAR ENTERITIDIS' named entity 'RECOMBINANT' named entity 'LACTOBACILLUS CASEI' named entity 'ANTIGEN' named entity 'PROTECTIVE IMMUNITY' named entity 'MICE' named entity 'PROVIDED' named entity 'SALMONELLA INFECTION' named entity 'ADJUVANT' named entity 'INDEPENDENT' named entity 'BUT' named entity 'INTRAGASTRIC' named entity 'ADDITION' named entity 'INDUCED' named entity 'EFFECT' named entity 'SALMONELLA ENTERICA SEROVAR ENTERITIDIS' named entity 'ANTIBODY' named entity 'EFFICACY' named entity 'MEDIATED' named entity 'ATTRIBUTABLE' named entity 'SERA' named entity 'FLAGELLIN' named entity 'PROTECTIVE IMMUNITY' named entity 'DID' named entity 'OBSERVED' named entity 'RECOMBINANT' named entity 'EITHER' covid:arg/6a109eb5b0e889ef933943ebf4db5c26cacf85b8 named entity 'antigen' named entity 'adjuvant' named entity 'IFN' named entity 'recombinant' named entity 'feces' named entity 'mice' named entity 'L. casei' named entity 'Lactobacillus casei' named entity 'recombinant' named entity 'antigen' named entity 'Salmonella enterica serovar Enteritidis' named entity 'coronavirus' named entity 'antigen' named entity 'infection' named entity 'centrifugation' named entity 'adjuvant' named entity 'absorbance' named entity 'L. casei' named entity 'lactobacilli' named entity 'antibody' named entity 'goat' named entity 'antigen' named entity 'FliC'

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