About: Trafficking motifs in the SARS-coronavirus nucleocapsid protein

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About: Trafficking motifs in the SARS-coronavirus nucleocapsid protein Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Trafficking motifs in the SARS-coronavirus nucleocapsid protein
Creator	You, Jae-Hwan Hiscox, Julian Reed, Mark
topic	covid:682a5929fdc17c1d46c59fb4813aa96c40ffcaf6#this
Source	Elsevier; Medline; PMC
abstract	Abstract The severe acute respiratory syndrome-coronavirus nucleocapsid (N) protein is involved in virus replication and modulation of cell processes. In this latter respect control may in part be achieved through the sub-cellular localisation of the protein. N protein predominately localises in the cytoplasm (the site of virus replication and assembly) but also in the nucleus/nucleolus. Using a combination of live-cell and confocal microscopy coupled to mutagenesis we identified a cryptic nucleolar localisation signal in the central part of the N protein. In addition, based on structural comparison to the avian coronavirus N protein, a nuclear export signal was identified in the C-terminal region of the protein.
has issue date	2007-07-13(xsd:dateTime)
bibo:doi	10.1016/j.bbrc.2007.05.036
bibo:pmid	17524366
has license	els-covid
sha1sum (hex)	682a5929fdc17c1d46c59fb4813aa96c40ffcaf6
schema:url	https://doi.org/10.1016/j.bbrc.2007.05.036
resource representing a document's title	Trafficking motifs in the SARS-coronavirus nucleocapsid protein
has PubMed Central identifier	PMC7092899
has PubMed identifier	17524366
schema:publication	Biochemical and Biophysical Research Communications
resource representing a document's body	covid:682a5929fdc17c1d46c59fb4813aa96c40ffcaf6#body_text
is http://vocab.deri.ie/void#inDataset of	https://covidontheweb.inria.fr:4443/about/id/http/ns.inria.fr/covid19/682a5929fdc17c1d46c59fb4813aa96c40ffcaf6
is schema:about of	named entity 'MOTIFS' named entity 'structural' named entity 'replication' named entity 'cytoplasm' named entity 'TRAFFICKING' named entity 'USING' named entity 'AVIAN CORONAVIRUS' named entity 'PROTEIN ' named entity 'COMPARISON' named entity 'LIVE' named entity 'RESPECT' named entity 'CONFOCAL MICROSCOPY' named entity 'BUT' named entity 'COMBINATION' named entity 'PREDOMINATELY' named entity 'NUCLEOCAPSID' named entity 'CELL' named entity 'NUCLEAR EXPORT SIGNAL' named entity 'CORONAVIRUS' named entity 'REGION' named entity 'ADDITION' named entity 'INVOLVED' named entity 'SITE OF' named entity 'N PROTEIN' named entity 'SEVERE ACUTE RESPIRATORY SYNDROME' named entity 'CENTRAL' named entity 'CONTROL' named entity 'BASED' named entity 'PROTEIN' named entity 'C-TERMINAL' named entity 'SUB-' named entity 'STRUCTURAL' named entity 'CELLULAR LOCALISATION' named entity 'ASSEMBLY' named entity 'SARS' named entity 'CORONAVIRUS' named entity 'LOCALISATION' named entity 'NUCLEOLAR' named entity 'NUCLEUS' named entity 'SIGNAL' named entity 'MUTAGENESIS' named entity 'COUPLED' named entity 'CELL PROCESSES' named entity 'VIRUS REPLICATION' named entity 'CRYPTIC' named entity 'MODULATION' named entity 'IDENTIFIED' named entity 'CYTOPLASM' named entity 'PART OF' named entity 'NUCLEOCAPSID PROTEIN' named entity 'nuclear export signal' named entity 'protein' named entity 'nucleocapsid' named entity 'nucleocapsid' named entity 'coronavirus' named entity 'nuclear export signal' named entity 'severe acute respiratory syndrome' named entity 'nucleus' named entity 'protein' named entity 'avian coronavirus' named entity 'nucleocapsid protein' named entity 'coronavirus' named entity 'combination' named entity 'protein' named entity 'amino acids' named entity 'region 1' named entity 'cytoplasm' named entity 'leucine' named entity 'C-terminally' named entity 'virus' named entity 'protein' named entity 'proteome' named entity 'nucleocapsid' named entity 'protein' named entity 'protein' named entity 'survivin' named entity 'nucleocapsid'

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