About: Microwave- and Heat-Based Decontamination of N95 Filtering Facepiece Respirators: A Systematic Review

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Microwave- and Heat-Based Decontamination of N95 Filtering Facepiece Respirators: A Systematic Review
Creator	Mcnally, Dayre Agarwal, Anirudh Agyei, Kwame Barrowman, ; Barrowman, Nick Chamberlain, Graham Dinh, Tri Gertsman, Shira Gibson, Jess Gibson, Ng James, ; Kwame, ; Mcnally, James Ng, Rhiannon O'hearn, Agarwal O'hearn, Katharine Sampson, Margaret Sikora, Lindsey Staykov, Emiliyan Tsampalieros, Anne Webster, ; Webster, Richard
Source	Elsevier; Medline; PMC
abstract	BACKGROUND: In pandemics such as COVID-19, shortages of personal protective equipment are common. One solution may be to decontaminate equipment such as facemasks for reuse. AIM: To collect and synthesize existing information on decontamination of N95 filtering facepiece respirators (FFRs) using microwave and heat-based treatments, with special attention to impact on mask function (aerosol penetration, airflow resistance), fit, and physical traits. METHODS: A systematic review (PROSPERO CRD42020177036) of literature available from Medline, Embase, Global Health, and other sources was conducted. Records were screened independently by two reviewers, and data was extracted from studies that reported on effects of microwave- or heat-based decontamination on N95 FFR performance, fit, physical traits, and/or reductions in microbial load. FINDINGS: Thirteen studies were included that used dry/moist microwave irradiation, heat, or autoclaving. All treatment types reduced pathogen load by a log10 reduction factor of at least three when applied for sufficient duration (>30s microwave, >60 min dry heat), with most studies assessing viral pathogens. Mask function (aerosol penetration <5% and airflow resistance <25mmH(2)O) was preserved after all treatments except autoclaving. Fit was maintained for most N95 models, though all treatment types caused observable physical damage to at least one model. CONCLUSIONS: Microwave irradiation and heat may be safe and effective viral decontamination options for N95 FFR reuse during critical shortages. The evidence does not support autoclaving or high-heat (>90(o)C) approaches. Physical degradation may be an issue for certain mask models, and more real-world evidence on fit is needed.
has issue date	2020-08-22(xsd:dateTime)
bibo:doi	10.1016/j.jhin.2020.08.016
bibo:pmid	32841704
has license	no-cc
sha1sum (hex)	68266bff7ec5cab0f3bf0d5541bcdd108e20c3d1
schema:url	https://doi.org/10.1016/j.jhin.2020.08.016
resource representing a document's title	Microwave- and Heat-Based Decontamination of N95 Filtering Facepiece Respirators: A Systematic Review
has PubMed Central identifier	PMC7443086
has PubMed identifier	32841704
schema:publication	J Hosp Infect
resource representing a document's body	covid:68266bff7ec5cab0f3bf0d5541bcdd108e20c3d1#body_text
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