About: COVID-19 in people with diabetes: understanding the reasons for worse outcomes

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About: COVID-19 in people with diabetes: understanding the reasons for worse outcomes Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	COVID-19 in people with diabetes: understanding the reasons for worse outcomes
Creator	Prato, Stefano Apicella, Matteo Campopiano, Maria Coppelli, Alberto Mantuano, Michele Mazoni, Laura
Source	Elsevier; Medline; PMC
abstract	Since the initial COVID-19 outbreak in China, much attention has focused on people with diabetes because of poor prognosis in those with the infection. Initial reports were mainly on people with type 2 diabetes, although recent surveys have shown that individuals with type 1 diabetes are also at risk of severe COVID-19. The reason for worse prognosis in people with diabetes is likely to be multifactorial, thus reflecting the syndromic nature of diabetes. Age, sex, ethnicity, comorbidities such as hypertension and cardiovascular disease, obesity, and a pro-inflammatory and pro-coagulative state all probably contribute to the risk of worse outcomes. Glucose-lowering agents and anti-viral treatments can modulate the risk, but limitations to their use and potential interactions with COVID-19 treatments should be carefully assessed. Finally, severe acute respiratory syndrome coronavirus 2 infection itself might represent a worsening factor for people with diabetes, as it can precipitate acute metabolic complications through direct negative effects on β-cell function. These effects on β-cell function might also cause diabetic ketoacidosis in individuals with diabetes, hyperglycaemia at hospital admission in individuals with unknown history of diabetes, and potentially new-onset diabetes.
has issue date	2020-07-17(xsd:dateTime)
bibo:doi	10.1016/s2213-8587(20)30238-2
bibo:pmid	32687793
has license	no-cc
sha1sum (hex)	679fc0eaf9277f0fccae493c85af63843eb86708
schema:url	https://doi.org/10.1016/s2213-8587%2820%2930238-2
resource representing a document's title	COVID-19 in people with diabetes: understanding the reasons for worse outcomes
has PubMed Central identifier	PMC7367664
has PubMed identifier	32687793
schema:publication	Lancet Diabetes Endocrinol
resource representing a document's body	covid:679fc0eaf9277f0fccae493c85af63843eb86708#body_text
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