About: Inflammatory and Coagulative Considerations for the Management of Orthopaedic Trauma Patients With COVID-19: A Review of the Current Evidence and Our Surgical Experience

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About: Inflammatory and Coagulative Considerations for the Management of Orthopaedic Trauma Patients With COVID-19: A Review of the Current Evidence and Our Surgical Experience Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Inflammatory and Coagulative Considerations for the Management of Orthopaedic Trauma Patients With COVID-19: A Review of the Current Evidence and Our Surgical Experience
Creator	Menendez, Mariano Moon, Andrew Moverman, Michael Pagani, Nicholas Puzzitiello, Richard Ryan, Scott
Source	Medline; PMC
abstract	Mounting evidence suggests that the pathogenesis of coronavirus disease 2019 (COVID-19) involves a hyperinflammatory response predisposing patients to thromboembolic disease and acute respiratory distress. In the setting of severe blunt trauma, damaged tissues induce a local and systemic inflammatory response through similar pathways to COVID-19. As such, patients with COVID-19 sustaining orthopaedic trauma injuries may have an amplified response to the traumatic insult because of their baseline hyperinflammatory and hypercoagulable states. These patients may have compromised physiological reserve to withstand the insult of surgical intervention before reaching clinical instability. In this article, we review the current evidence regarding pathogenesis of COVID-19 and its implications on the management of orthopaedic trauma patients by discussing a case and the most recent literature.
has issue date	2020-05-14(xsd:dateTime)
bibo:doi	10.1097/bot.0000000000001842
bibo:pmid	32427809
has license	no-cc
sha1sum (hex)	676dbd0b4cbab767669069380ec6828e44b1c7d8
schema:url	https://doi.org/10.1097/bot.0000000000001842
resource representing a document's title	Inflammatory and Coagulative Considerations for the Management of Orthopaedic Trauma Patients With COVID-19: A Review of the Current Evidence and Our Surgical Experience
has PubMed Central identifier	PMC7302072
has PubMed identifier	32427809
schema:publication	J Orthop Trauma
resource representing a document's body	covid:676dbd0b4cbab767669069380ec6828e44b1c7d8#body_text
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