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About:
Towards effective COVID-19 vaccines: Updates, perspectives and challenges (Review)
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An Entity of Type :
schema:ScholarlyArticle
, within Data Space :
covidontheweb.inria.fr
associated with source
document(s)
Type:
Academic Article
research paper
schema:ScholarlyArticle
New Facet based on Instances of this Class
Attributes
Values
type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
title
Towards effective COVID-19 vaccines: Updates, perspectives and challenges (Review)
Creator
Carvalho, FĂ©lix
Kostoff, Ronald
Calina, Daniela
Egorov, Alex
Gabibov, Alexsandr
Ishmukhametov, Aydar
Oana Docea, Anca
Petrakis,
Shtilman, Michael
Spandidos, A
Tsatsakis, Aristidis
Vinceti, Marco
source
Medline; PMC
abstract
In the current context of the pandemic triggered by SARS-COV-2, the immunization of the population through vaccination is recognized as a public health priority. In the case of SARS-COV-2, the genetic sequencing was done quickly, in one month. Since then, worldwide research has focused on obtaining a vaccine. This has a major economic impact because new technological platforms and advanced genetic engineering procedures are required to obtain a COVID-19 vaccine. The most difficult scientific challenge for this future vaccine obtained in the laboratory is the proof of clinical safety and efficacy. The biggest challenge of manufacturing is the construction and validation of production platforms capable of making the vaccine on a large scale.
has issue date
2020-05-06
(
xsd:dateTime
)
bibo:doi
10.3892/ijmm.2020.4596
bibo:pmid
32377694
has license
cc-by-nc-nd
sha1sum (hex)
671d914b3e705e3e8bff9fe93a4d7b4bdd7a217a
schema:url
https://doi.org/10.3892/ijmm.2020.4596
resource representing a document's title
Towards effective COVID-19 vaccines: Updates, perspectives and challenges (Review)
has PubMed Central identifier
PMC7255458
has PubMed identifier
32377694
schema:publication
Int J Mol Med
resource representing a document's body
covid:671d914b3e705e3e8bff9fe93a4d7b4bdd7a217a#body_text
is
schema:about
of
named entity 'vaccine'
named entity 'The'
named entity 'This'
named entity 'MANUFACTURING'
named entity 'SEQUENCING'
named entity 'SARS-cOV-2'
named entity 'safety'
named entity 'technological'
named entity 'vaccine'
named entity 'genetic engineering'
named entity 'vaccination'
named entity 'vaccine'
named entity 'vaccine'
named entity 'SARS-cOV-2'
named entity 'production platforms'
named entity 'immunization'
named entity 'genetic engineering'
named entity 'cOVId-19'
named entity 'vaccine'
named entity 'economic'
named entity 'efficacy'
named entity 'cOVId-19'
named entity 'clinical development'
named entity 'preclinical'
named entity 'clinical trials'
named entity 'vaccination'
named entity 'RNA'
named entity 'hygiene'
named entity 'healthcare systems'
named entity 'tocilizumab'
named entity 'protein'
named entity 'antigen'
named entity 'Risk factors'
named entity 'gastrointestinal'
named entity 'vaccination'
named entity 'Preclinical'
named entity 'nucleocapsid'
named entity 'controlled conditions'
named entity 'virus'
named entity 'cOVId-19'
named entity 'immune dysfunction'
named entity 'developed countries'
named entity 'MERS'
named entity 'vaccine'
named entity 'inflammation'
named entity 'SARS'
named entity 'coronavirus'
named entity 'signs of disease'
named entity 'vaccine'
named entity 'adverse reactions'
named entity 'coronavirus'
named entity 'protein'
named entity 'vaccine'
named entity 'gene'
named entity 'epidemic'
named entity 'SARS-cOV-2'
named entity 'Adjuvant'
named entity 'vaccine'
named entity 'SV40'
named entity 'vaccine'
named entity 'SARS'
named entity 'SARS-cOV-2'
named entity 'SARS-cOV-2'
named entity 'cell receptor'
named entity 'SARS-CoV'
named entity 'weakened immune systems'
named entity 'vaccine'
named entity 'recombinant proteins'
named entity 'virus'
named entity 'AcE2'
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