About: Wrapping Things up about Virus RNA Replication

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Wrapping Things up about Virus RNA Replication
Creator	Mackenzie, Jason Munksgaard, Blackwell
Source	Medline; PMC
abstract	All single‐stranded ‘positive‐sense’ RNA viruses that infect mammalian, insect or plant cells rearrange internal cellular membranes to provide an environment facilitating virus replication. A striking feature of these unique membrane structures is the induction of 70–100 nm vesicles (either free within the cytoplasm, associated with other induced vesicles or bound within a surrounding membrane) harbouring the viral replication complex (RC). Although similar in appearance, the cellular composition of these vesicles appears to vary for different viruses, implying different organelle origins for the intracellular sites of viral RNA replication. Genetic analysis has revealed that induction of these membrane structures can be attributed to a particular viral gene product, usually a non‐structural protein. This review will highlight our current knowledge of the formation and composition of virus RCs and describe some of the similarities and differences in RNA‐membrane interactions observed between the virus families Flaviviridae and Picornaviridae.
has issue date	2005-09-05(xsd:dateTime)
bibo:doi	10.1111/j.1600-0854.2005.00339.x
bibo:pmid	16190978
has license	no-cc
sha1sum (hex)	66c9ad44dd45402add7d93ad24cbe0eda80928fe
schema:url	https://doi.org/10.1111/j.1600-0854.2005.00339.x
resource representing a document's title	Wrapping Things up about Virus RNA Replication
has PubMed Central identifier	PMC7169867
has PubMed identifier	16190978
schema:publication	Traffic
resource representing a document's body	covid:66c9ad44dd45402add7d93ad24cbe0eda80928fe#body_text
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