About: The MultiBac Baculovirus/Insect Cell Expression Vector System for Producing Complex Protein Biologics

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About: The MultiBac Baculovirus/Insect Cell Expression Vector System for Producing Complex Protein Biologics Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	The MultiBac Baculovirus/Insect Cell Expression Vector System for Producing Complex Protein Biologics
Creator	Berger, Imre Garzoni, Frederic Fitzgerald, D Gupta, • Aubert, Alice Drncová, Petra Aubert, • Fitzgerald, Daniel Gupta, Kapil Drncová, P Garzoni European, • Raj, Govinda Raj, • Sari, D Sari, Duygu Thimiri, Balaji
Source	Medline; PMC
abstract	Multiprotein complexes regulate most if not all cellular functions. Elucidating the structure and function of these complex cellular machines is essential for understanding biology. Moreover, multiprotein complexes by themselves constitute powerful reagents as biologics for the prevention and treatment of human diseases. Recombinant production by the baculovirus/insect cell expression system is particularly useful for expressing proteins of eukaryotic origin and their complexes. MultiBac, an advanced baculovirus/insect cell system, has been widely adopted in the last decade to produce multiprotein complexes with many subunits that were hitherto inaccessible, for academic and industrial research and development. The MultiBac system, its development and numerous applications are presented. Future opportunities for utilizing MultiBac to catalyze discovery are outlined.
has issue date	2015-12-12(xsd:dateTime)
bibo:doi	10.1007/978-3-319-27216-0_13
bibo:pmid	27165327
has license	no-cc
sha1sum (hex)	664ab04b30451c3bd58f74ef061fcb78dd4c7575
schema:url	https://doi.org/10.1007/978-3-319-27216-0_13
resource representing a document's title	The MultiBac Baculovirus/Insect Cell Expression Vector System for Producing Complex Protein Biologics
has PubMed Central identifier	PMC7122245
has PubMed identifier	27165327
schema:publication	Advanced Technologies for Protein Complex Production and Characterization
resource representing a document's body	covid:664ab04b30451c3bd58f74ef061fcb78dd4c7575#body_text
is schema:about of	named entity 'Future' named entity 'cell' named entity 'eukaryotic' named entity 'opportunities' named entity 'multiprotein complexes' named entity 'MULTIPROTEIN COMPLEXES' named entity 'ITS' named entity 'MACHINES' named entity 'ADVANCED' named entity 'REGULATE' named entity 'THESE' named entity 'ADVANCED' named entity 'BACULOVIRUS' named entity 'EXPRESSION SYSTEM' named entity 'CELLULAR' named entity 'STRUCTURE' named entity 'PROTEINS' named entity 'USEFUL' named entity 'APPLICATIONS' named entity 'TECHNOLOGIES' named entity 'CELL' named entity 'EUKARYOTIC' named entity 'FUNCTIONS' named entity 'PREVENTION' named entity 'PROTEIN COMPLEX' named entity 'PRODUCTION' named entity 'CHARACTERIZATION' named entity 'BIOLOGICS' named entity 'PRODUCTION' named entity 'HUMAN DISEASES' named entity 'POWERFUL' named entity 'FUNCTION' named entity 'THEIR' named entity 'INDUSTRIAL RESEARCH' named entity 'ADOPTED' named entity 'SYSTEM' named entity 'FUTURE' named entity 'UNDERSTANDING' named entity 'CELL SYSTEM' named entity 'TREATMENT' named entity 'BIOLOGY' named entity 'PRESENTED' named entity 'ACADEMIC' named entity 'ORIGIN' named entity 'REAGENTS' named entity 'DECADE' named entity 'DEVELOPMENT' named entity 'DISCOVERY' named entity 'RECOMBINANT' named entity 'TO PRODUCE' named entity 'NUMEROUS' named entity 'COMPLEXES' named entity 'COMPLEX' named entity 'ESSENTIAL' named entity 'RESEARCH AND DEVELOPMENT' covid:arg/664ab04b30451c3bd58f74ef061fcb78dd4c7575 named entity 'diseases' named entity 'human' named entity 'insect' named entity 'applications' named entity 'Recombinant' named entity 'subunits' named entity 'baculovirus' named entity 'structure' named entity 'cell' named entity 'Recombinant'

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