About: Expression and function of chemokines during viral infections: from molecular mechanisms to in vivo function

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About: Expression and function of chemokines during viral infections: from molecular mechanisms to in vivo function Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Expression and function of chemokines during viral infections: from molecular mechanisms to in vivo function
Creator	Paludan, Søren Melchjorsen, Jesper Sørensen, Louise
Source	PMC
abstract	Recruitment and activation of leukocytes are important for elimination of microbes, including viruses, from infected areas. Chemokines constitute a group of bioactive peptides that regulate leukocyte migration and also contribute to activation of these cells. Chemokines are essential mediators of inflammation and important for control of viral infections. The profile of chemokine expression contributes to shaping the immune response during viral infection, whereas viral subversion of the chemokine system allows the virus to evade antiviral activities of the host. In this review, we discuss the role of chemokines in host‐defense against virus infections, and we also look deeper into the virus‐cell interactions that trigger chemokine expression as well as the cellular signaling cascades involved.
has issue date	2003-06-16(xsd:dateTime)
bibo:doi	10.1189/jlb.1102577
bibo:pmid	12949236
has license	no-cc
sha1sum (hex)	646b45e9f90b7e76a848e3d7da0d7ff405f7ad2a
schema:url	https://doi.org/10.1189/jlb.1102577
resource representing a document's title	Expression and function of chemokines during viral infections: from molecular mechanisms to in vivo function
has PubMed Central identifier	PMC7166880
has PubMed identifier	12949236
schema:publication	J Leukoc Biol
resource representing a document's body	covid:646b45e9f90b7e76a848e3d7da0d7ff405f7ad2a#body_text
is schema:about of	named entity 'virus-cell interactions' named entity 'involved' named entity 'chemokine' named entity 'expression' named entity 'activities' named entity 'cells' named entity 'Chemokines' named entity 'molecular mechanisms' named entity 'REGULATE' named entity 'EXPRESSION' named entity 'CHEMOKINE' named entity 'CONTROL' named entity 'LOOK' named entity 'ACTIVATION' named entity 'ELIMINATION' named entity 'bioactive' named entity 'The profile' named entity 'migration' named entity 'virus infections' named entity 'chemokine' named entity 'immune response' named entity 'host-defense' named entity 'antiviral' named entity 'Chemokines' named entity 'Chemokines' named entity 'virus' named entity 'viral infections' named entity 'CCL2' named entity 'EBV' named entity 'molecular mechanisms' named entity 'influenza virus' named entity 'CCL2' named entity 'PVM' named entity 'ATF2' named entity 'antibody' named entity 'viral proteins' named entity 'intracellular' named entity 'oxidative stress' named entity 'CXCL10' named entity 'cytokines' named entity 'HSV-1' named entity 'virus' named entity 'IRFs' named entity 'host cell' named entity 'immunopathology' named entity 'DCs' named entity 'IRF-3' named entity 'kinase' named entity 'herpesvirus' named entity 'neutrophils' named entity 'apoptotic cells' named entity 'chemokine' named entity 'dsRNA' named entity 'dsRNA' named entity 'wild-type' named entity 'chemokine' named entity 'HSV-1' named entity 'serine/threonine' named entity 'signal transduction' named entity 'infection' named entity 'chemokines' named entity 'IFN' named entity 'IRFs' named entity 'CCL3' named entity 'IRF-3' named entity 'CD4' named entity 'IRF-3' named entity 'chemokines' named entity 'signal-transduction pathways' named entity 'virus' named entity 'signal transduction' named entity 'leukocytes' named entity 'leukocytes' named entity 'ligand' named entity 'transcription factors' named entity 'IRF-3' named entity 'HSV-2' named entity 'chemokines' named entity 'Liver disease'

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