About: Sequential circulation of canine adenoviruses 1 and 2 in captive wild carnivores, France

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About: Sequential circulation of canine adenoviruses 1 and 2 in captive wild carnivores, France Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Sequential circulation of canine adenoviruses 1 and 2 in captive wild carnivores, France
Creator	Buonavoglia, Canio Decaro, Nicola Martella, Vito Losurdo, Michele Lanave, Gianvito Dowgier, Giulia Varello, Katia Lucente, Maria Ventriglia, Gianluca Bozzetta, Elena Lahoreau, Jennifer
Source	Elsevier; Medline; PMC
abstract	Scarce data are currently available about the ecology of canine adenoviruses (CAdVs) in wild carnivores. In this paper, the consecutive circulation of CAdV-1 and CAdV-2 in wild carnivores maintained in a French zoological park is reported. A fatal CAdV-1 infection was observed in a Eurasian wolf (Canis lupus lupus), which displayed gross lesions, histopathological changes and immunohistochemical findings suggestive of CAdV-1 infection. The virus was isolated on cell cultures and its genome was determined through next-generation sequencing, resulting genetically related to a recent Italian CAdV-1 strain detected in an Italian wolf. Subsequently, subclinical circulation of CAdV-2 was demonstrated by molecular methods in wild carnivores maintained in the same zoological park, some of which had been previously vaccinated with a CAdV-2 vaccine. Virus detection at a long distance from vaccination and by unvaccinated animals was suggestive of infection by a CAdV-2 field strain, although no data are available about the extent and duration of shedding of CAdV-2 modified-live virus in wild or domestic carnivores. The present paper provides new insights into the CAdV ecology in wildlife, although future studies are needed to fully understand the pathogenic potential of both CAdVs especially in endangered carnivore species.
has issue date	2018-05-31(xsd:dateTime)
bibo:doi	10.1016/j.vetmic.2018.05.025
bibo:pmid	29981710
has license	no-cc
sha1sum (hex)	62dc12ce03cae962f93564a85f420272184a6712
schema:url	https://doi.org/10.1016/j.vetmic.2018.05.025
resource representing a document's title	Sequential circulation of canine adenoviruses 1 and 2 in captive wild carnivores, France
has PubMed Central identifier	PMC7172945
has PubMed identifier	29981710
schema:publication	Vet Microbiol
resource representing a document's body	covid:62dc12ce03cae962f93564a85f420272184a6712#body_text
is schema:about of	named entity 'canine' named entity 'France' named entity 'carnivore' named entity 'urine' named entity 'Geneious' named entity 'carnivore' named entity 'Tissues' named entity 'domestic dogs' named entity '8/11' named entity 'Italy' named entity 'timber wolf' named entity 'Geneious' named entity 'foetal bovine serum' named entity 'zoological park' named entity 'gamma distribution' named entity 'red foxes' named entity 'antibody' named entity 'QIAGEN' named entity 'intranuclear inclusions' named entity 'subclinical' named entity 'Italian' named entity 'hexon' named entity 'antibodies' named entity 'FBS' named entity 'modified-live' named entity 'spp' named entity 'Fig' named entity 'adenovirus' named entity 'Fig' named entity 'wild animals' named entity 'zoological park' named entity 'infection' named entity 'zoological park' named entity 'brown bear' named entity 'Canidae' named entity 'Illumina' named entity 'serological survey' named entity 'feline' named entity 'Eurasian wolves' named entity 'viral particles' named entity 'Vulpes vulpes' named entity 'genus' named entity 'uveitis' named entity 'virus' named entity 'kidney' named entity 'red fox' named entity 'carnivore' named entity 'canine' named entity 'blood agar' named entity 'intestine' named entity 'methionine' named entity 'carnivore' named entity 'reference genome' named entity 'virus' named entity 'red foxes' named entity 'domestic animals' named entity 'Real-time PCR' named entity 'haemorrhagic' named entity 'liver' named entity 'Italy' named entity 'wild species' named entity 'Nucleic acids' named entity 'CLL' named entity 'genome' named entity 'wild carnivores' named entity 'red fox' named entity 'w/v' named entity 'internal organs' named entity 'canids' named entity 'GenBank' named entity 'zoological park'

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