About: One-year mortality and predictors of death among hospital survivors of acute respiratory distress syndrome

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About: One-year mortality and predictors of death among hospital survivors of acute respiratory distress syndrome Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	One-year mortality and predictors of death among hospital survivors of acute respiratory distress syndrome
Creator	Wang, Chen Matthay, Michael Zhuo, Hanjing Bernard, Gordon Calfee, Carolyn May, Addison Wang, C Ware, Lorraine Janz, David Kangelaris, Kirsten May, A Paul, Devon Bernard, Á Calfee, C Janz, Á Kangelaris, K Matthay, M Paul, D Ware, L Ware, Á Zhuo, Á
Source	PMC
abstract	PURPOSE: Advances in supportive care and ventilator management for acute respiratory distress syndrome (ARDS) have resulted in declines in short-term mortality, but risks of death after survival to hospital discharge have not been well described. Our objective was to quantify the difference between short-term and long-term mortality in ARDS and to identify risk factors for death and causes of death at 1 year among hospital survivors. METHODS: This multi-intensive care unit, prospective cohort included patients with ARDS enrolled between January 2006 and February 2010. We determined the clinical characteristics associated with in-hospital and 1-year mortality among hospital survivors and utilized death certificate data to identify causes of death. RESULTS: Of 646 patients hospitalized with ARDS, mortality at 1 year was substantially higher (41 %, 95 % CI 37–45 %) than in-hospital mortality (24 %, 95 % CI 21–27 %), P < 0.0001. Among 493 patients who survived to hospital discharge, the 110 (22 %) who died in the subsequent year were older (P < 0.001) and more likely to have been discharged to a nursing home, other hospital, or hospice compared to patients alive at 1 year (P < 0.001). Important predictors of death among hospital survivors were comorbidities present at the time of ARDS, and not living at home prior to admission. ARDS-related measures of severity of illness did not emerge as independent predictors of mortality in hospital survivors. CONCLUSIONS: Despite improvements in short-term ARDS outcomes, 1-year mortality is high, mostly because of the large burden of comorbidities, which are prevalent in patients with ARDS. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s00134-013-3186-3) contains supplementary material, which is available to authorized users.
has issue date	2014-01-17(xsd:dateTime)
bibo:doi	10.1007/s00134-013-3186-3
bibo:pmid	24435201
has license	no-cc
sha1sum (hex)	621bc47a50ac44b105a2e24469dedb155531de6f
schema:url	https://doi.org/10.1007/s00134-013-3186-3
resource representing a document's title	One-year mortality and predictors of death among hospital survivors of acute respiratory distress syndrome
has PubMed Central identifier	PMC3943651
has PubMed identifier	24435201
schema:publication	Intensive Care Med
resource representing a document's body	covid:621bc47a50ac44b105a2e24469dedb155531de6f#body_text
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